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hemoglobin Mizuho

Leu replaced by Pro at position 68(E12) of the beta chain

Also Known As:

Hb Mizuho; Hemoglobin Mizuho

Networked: 5 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Hemoglobins: 37188
      - Abnormal Hemoglobins: 120
        hemoglobin Mizuho: 5
  - Hemeproteins: 194
    - Globins: 2716
      - Hemoglobins: 37188
        Abnormal Hemoglobins: 120
        hemoglobin Mizuho: 5

Experts

1.	Diepold, Miriam: 1 article (07/2021)
2.	Keller, Peter: 1 article (07/2021)
3.	Medri, Cesare: 1 article (07/2021)
4.	Njue, Linet: 1 article (07/2021)
5.	Rovó, Alicia: 1 article (07/2021)
6.	Taleghani, Behrouz Mansouri: 1 article (07/2021)

Related Diseases

1.	Hemolytic Anemia 01/01/1990 - "Hb Mizuho [beta 68(E12)Leu----Pro] was identified in a child of Italian/Sicilian descent who exhibited severe, transfusion dependent hemolytic anemia which improved following splenectomy. " 01/01/1977 - "Hemoglobin Mizuho or beta 68 (E 12) leucine leads to proline, a new unstable variant associated with severe hemolytic anemia."
2.	Reticulocytosis 11/24/2023 - "Extreme Reticulocytosis After Splenectomy in a Patient With Hemoglobin Mizuho."
3.	Iron Overload 07/01/2021 - "Iron overload in Hb Mizuho patients seems to be mainly attributed to transfusions and has less to do with ineffective erythropoiesis. "
4.	Hemoglobinopathies 06/14/2023 - "[Allogeneic hematopoietic stem cell transplantation in Hb Mizuho of unstable hemoglobinopathy: a case report]."

Related Drugs and Biologics

1.	leucylproline
2.	Proline (L-Proline)
3.	Leucine (L-Leucine)

Related Therapies and Procedures

1.	Splenectomy
2.	Hematopoietic Stem Cell Transplantation