artonin E

08/01/2013 - "The anti-migration and anti-invasion activities of artonin E, extracted from bark of Artocarpus gomezianus, were investigated in lung cancer cells in this study. "
08/01/2013 - "Artonin E inhibited invasion and migration of other lung cancer cells, namely H292, H23 and A549 cells. "
08/01/2013 - "Effects of artonin e on migration and invasion capabilities of human lung cancer cells."
12/01/2012 - "Artonin E mediates MCL1 down-regulation and sensitizes lung cancer cells to anoikis."
12/01/2012 - "Since lung cancer cells possess an ability to resist anoikis, resulting in a high rate of metastasis and death, the present study aimed to investigate the possible anoikis-sensitizing effect of artonin E (AE). "

01/01/2017 - "In this study, we investigated the cytotoxic mechanism of Artonin E in MCF-7 breast cancer cells, which has so far not been reported. "
01/01/2017 - "Artonin E, was seen to effectively relinquish MDA-MB 231 breast cancer cells of their apoptosis evading capacity, causing a half-maximal growth inhibition at low concentrations (14.3, 13.9 and 9.8 μM) after the tested time points (24, 48 and 72 hours), respectively. "
01/01/2017 - "In all, Artonin E stood high as a potential agent in the treatment of breast cancer."
01/01/2017 - "In this context, Artonin E significantly suppressed the breast cancer cell's viability while inducing apoptosis in a dose-dependent manner. "
06/29/2016 - "Artonin E and Structural Analogs from Artocarpus Species Abrogates Estrogen Receptor Signaling in Breast Cancer."

04/01/2019 - "TRAIL-refractory cancer (LoVo cells) was treated with artonin E and TRAIL. "
01/01/2017 - "This study was conducted to investigate the mechanism of inhibition of Artonin E, a prenylated flavonoid on MDA-MB 231 triple negative breast cancer cell, with a view of mitigating the hallmarks displayed by these tumors. "
04/01/2019 - "In an effort to overcome TRAIL-refractory cancer, we investigated the effect of artonin E in regulating death receptor 5 (DR5) and cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein (cFLIP), two major mediators regulate TRAIL-induced apoptosis, in LoVo cells as a model of TRAIL refractory CRC. "

08/01/2013 - "These results suggest that artonin E may be a promising candidate for anti-metastasis use."
12/01/2012 - "Since lung cancer cells possess an ability to resist anoikis, resulting in a high rate of metastasis and death, the present study aimed to investigate the possible anoikis-sensitizing effect of artonin E (AE). "

01/01/2017 - "In all, Artonin E showed the potential as a promising candidate to combat the aggressive triple negative breast cancer."
01/01/2017 - "The molecular mechanism of the anticancer effect of Artonin E in MDA-MB 231 triple negative breast cancer cells."
01/01/2017 - "This study was conducted to investigate the mechanism of inhibition of Artonin E, a prenylated flavonoid on MDA-MB 231 triple negative breast cancer cell, with a view of mitigating the hallmarks displayed by these tumors. "