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2- oxo- 1,2,3,6- tetrahydropyrimidine- 4,6- dicarboxylate

structure given in first source

Also Known As:

HDDP

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidinones: 71
      - Uracil: 1493
        Orotic Acid: 384
        2-oxo-1,2,3,6-tetrahydropyrimidine-4,6-dicarboxylate: 6
- Heterocyclic Acids
  - Orotic Acid: 384
    - 2-oxo-1,2,3,6-tetrahydropyrimidine-4,6-dicarboxylate: 6

Experts

1.	Lin, Chun-Li: 2 articles (10/2021 - 06/2020)
2.	Liu, Hsuan-Chih: 1 article (10/2021)
3.	Zeng, Yu-Hui: 1 article (10/2021)
4.	Honma, Yoshitaka: 1 article (01/2021)
5.	Igaki, Hiroshi: 1 article (01/2021)
6.	Inaba, Koji: 1 article (01/2021)
7.	Itami, Jun: 1 article (01/2021)
8.	Ito, Kimiteru: 1 article (01/2021)
9.	Kashihara, Tairo: 1 article (01/2021)
10.	Kato, Ken: 1 article (01/2021)

Related Diseases

1.	Wrist Fractures 10/18/2021 - "This study compares the absolute and relative stabilities of a novel hybrid dorsal double plating (HDDP) to the often-used dorsal double plating (DDP) under distal radius fracture. " 06/01/2020 - "Simulation results showed that the bone plate stress values for the distal radius fractures fixed with HDDP was much smaller than those with DDP regardless of the type of bone fractures and load conditions. "
2.	Bone Fractures (Bone Fracture) 06/01/2020 - "Simulation results showed that the bone plate stress values for the distal radius fractures fixed with HDDP was much smaller than those with DDP regardless of the type of bone fractures and load conditions. "
3.	Hepatoblastoma 08/15/2002 - "To estimate the disease-response rate, proportion of patients whose tumors can be made resectable, event-free survival (EFS), and toxicity in children with unresectable or metastatic hepatoblastoma (HB) after sequential treatment with the following: (1) carboplatin (CARBO); (2) CARBO, vincristine, and fluorouracil (CARBO-VCR-5-FU); and (3) high-dose cisplatin and etoposide (HDDP-ETOP). "
4.	Neoplasms (Cancer) 08/15/2002 - "Children whose tumors remained unresectable after CARBO-VCR-5-FU or who demonstrated no response or progressive disease during this therapy received two courses of HDDP (40 mg/m(2)/d), days 1 to 5; and ETOP (100 mg/m(2)/d), days 2 to 4. Five-year EFS estimates were 59% +/- 11% for stage III disease (n = 22) and 27% +/- 16% for stage IV disease (n = 11), respectively (P =.037). " 08/15/2002 - "To estimate the disease-response rate, proportion of patients whose tumors can be made resectable, event-free survival (EFS), and toxicity in children with unresectable or metastatic hepatoblastoma (HB) after sequential treatment with the following: (1) carboplatin (CARBO); (2) CARBO, vincristine, and fluorouracil (CARBO-VCR-5-FU); and (3) high-dose cisplatin and etoposide (HDDP-ETOP). "
5.	Lymphatic Metastasis 01/01/2021 - "Our initial experience of IIHDP VMAT suggested that IIHDP VMAT to treat HNSCC neck lymph node metastases measuring ≥ 2 cm was feasible and possibly led to better local control than HDDP VMAT."

Related Drugs and Biologics

1.	Glucagon-Like Peptide 1 (GLP 1)
2.	Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)
3.	Carboplatin (JM8)
4.	Vincristine (Oncovin)
5.	Fluorouracil (Carac)
6.	Etoposide (VP 16)
7.	Esters
8.	Cisplatin (Platino)
9.	Acids
10.	F 382

Related Therapies and Procedures

1.	Therapeutics
2.	Bone Plates (Bone Plate)