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5- ((2- (diethylamino)ethyl)amino)- 7- methoxy- 5,11- dihydro(1)benzoxepino(3,4- b)pyridine

structure given in first source

Also Known As:

5-((2-(diethylamino)ethyl)amino)-7-methoxy-5,11-dihydro(1)benzoxepino(3,4-b)pyridine 1.5 fumarate; DEAMBP; KW 3407; KW-3407; KW3407

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzoxepins: 1
      - 5-((2-(diethylamino)ethyl)amino)-7-methoxy-5,11-dihydro(1)benzoxepino(3,4-b)pyridine: 2

Related Diseases

1.	Mydriasis 11/01/1990 - "Compound 9,5-[[2-(diethylamino)ethyl]amino]-7-methoxy-5,11-dihydro[1] benzoxepino[3,4-b]pyridine 1.5-fumarate, which exhibited low affinity for muscarinic acetylcholine receptors and a high ED100(mydriasis)/ED50(antiarrhythmic activity) ratio, was selected for further development and clinical evaluation as KW-3407. "
2.	Cardiac Arrhythmias (Arrythmia) 08/01/1992 - "[Effects of a new antiarrhythmic drug, KW-3407, on canine ventricular arrhythmia models]." 08/01/1992 - "KW-3407, 20 mg/kg/10 min, suppressed these three arrhythmia models, similar to flecainide, mexiletine and phenytoin. "

Related Drugs and Biologics

1.	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)
2.	Phenytoin (Dilantin)
3.	Mexiletine (Mexitil)
4.	Flecainide (Tambocor)
5.	Anti-Arrhythmia Agents
6.	benzocycloheptapyridine