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poliovirus receptor

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an ortholog of mouse Tage4; used by poliovirus to bind and enter the cell; RefSeq NM_006505 (human)

Also Known As:

CD155 protein; CD155 protein, human; HVED protein, human; NECL5 protein, human; PVR protein, human; TAGE4 protein, human; nectin-like-5 protein, human; poliovirus receptor, human; poliovirus receptors; receptor, poliovirus

Networked: 85 relevant articles (1 outcomes, 7 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins
- Proteins: 90489
  - Membrane Proteins: 5300
    - Cell Surface Receptors: 753
      - Virus Receptors: 59
        poliovirus receptor: 85

Experts

1.	Takai, Yoshimi: 6 articles (06/2007 - 08/2004)
2.	Ikeda, Wataru: 6 articles (06/2007 - 08/2004)
3.	Gromeier, Matthias: 4 articles (03/2012 - 07/2004)
4.	Minami, Yukiko: 4 articles (06/2007 - 08/2004)
5.	Kajita, Mihoko: 4 articles (06/2007 - 10/2005)
6.	Fujito, Tsutomu: 4 articles (06/2007 - 08/2004)
7.	Lopez, Marc: 3 articles (12/2014 - 07/2002)
8.	Moretta, Alessandro: 3 articles (01/2014 - 05/2004)
9.	Koike, Satoshi: 3 articles (01/2012 - 03/2004)
10.	Nagata, Noriyo: 3 articles (01/2012 - 03/2004)

Related Diseases

1.	Infection 10/15/1996 - "Greater than 90% of monocytes express the poliovirus receptor but only 6% of these cells are susceptible to poliovirus infection, making this a good system to study blocks to poliovirus replication. " 05/25/1995 - "Because a prerequisite for infection of a cell with the poliovirus is the presence of poliovirus receptor (PVR), we examined its tissue localization in the human muscle, spinal cord, and muscle cultures using a specific monoclonal antibody against PVR in immunocytochemical studies on serial sections. " 09/15/2005 - "One such virus, poliovirus (PV), is an extremely lytic RNA virus that requires the expression of CD155, the poliovirus receptor (PVR), for infection. " 01/20/2005 - "Murine L20B cells expressing human poliovirus receptor responded to the infection by both CPE and apoptosis concurrently. " 01/01/2005 - "Expression of the poliovirus receptor (PVR) on cells is a major host determinant of infection by poliovirus. "
2.	Cleft Lip (Harelip) 01/01/2009 - "To study the relationship of nonsyndromic cleft lip and/or palate (NSCL/P) and poliovirus receptor-related 1 exon3 (PVRL1exon3) polymorphisms in Han People of Jiangzhe area. " 10/01/2005 - "The aim of this study was to determine the sequence changes of the Cleft Lip and Palate Transmembrane Protein 1 (CLPTM 1) and Poliovirus Receptor Related 1 (PVRL 1) genes in patients with non-syndromic complete clefts of lip, alveolus and palate and to correlate these findings with clinical features. " 01/01/2009 - "[Relationship of nonsyndromic cleft lip and/or palate and poliovirus receptor-related 1 exon 3 polymorphisms in Han people of Jiangzhe area]." 06/01/2008 - "Study of the poliovirus receptor related-1 gene in Thai patients with non-syndromic cleft lip with or without cleft palate." 11/01/2010 - "Association analysis of the poliovirus receptor related-2 gene in patients with nonsyndromic cleft lip with or without cleft palate."
3.	Cleft Palate (Palate, Cleft) 06/01/2008 - "Study of the poliovirus receptor related-1 gene in Thai patients with non-syndromic cleft lip with or without cleft palate." 11/01/2010 - "Association analysis of the poliovirus receptor related-2 gene in patients with nonsyndromic cleft lip with or without cleft palate." 07/01/2012 - "The poliovirus receptor related-1 (PVRL1) gene encodes nectin-1, a cell-cell adhesion molecule (OMIM #600644), and is mutated in the cleft lip with or without cleft palate/ectodermal dysplasia-1 syndrome (CLPED1, OMIM #225000). "
4.	Multiple Myeloma 01/01/2015 - "In this study, we investigated the effect of different nitric oxide (NO) donors on the expression of the DNAM-1 ligand Poliovirus Receptor/CD155 (PVR/CD155) in multiple myeloma (MM) cells. "
5.	Lymphoid Leukemia 12/01/2011 - "The aim of this study was to identify if the expression of poliovirus receptor (PVR) on the surface of acute B lymphoid leukemia (B-ALL) cells RS4:11 and SUP-B15 is modulated by epigenetic mechanism. " 12/01/2011 - "[Poliovirus receptor on surface of acute B lymphoid leukemia cells modulated by epigenetic mechanism]."

Related Drugs and Biologics

1.	Toll-Like Receptors (Toll-Like Receptor)
2.	Nitric Oxide (Nitrogen Monoxide)
3.	nectins
4.	Immunoglobulins (Immunoglobulin)
5.	Ligands
6.	Zlotogora syndrome
7.	Interferon-beta
8.	Proteins (Proteins, Gene)
9.	DNA (Deoxyribonucleic Acid)
10.	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)

Related Therapies and Procedures

1.	Intraperitoneal Injections