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hinesol (agarospirol)

from Atractylodes Lance rhizome; RN given refers to (2R-(2alpha,5alpha(S*)))-isomer

Also Known As:

agarospirol; 2R-(2alpha,5beta)(R*)-isomer of hinesol

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - hinesol: 4
  - Cyclic Hydrocarbons: 97
    - Spiro Compounds: 2
      - hinesol: 4
Polycyclic Compounds: 6
- Spiro Compounds: 2
  - hinesol: 4

Experts

1.	Chhipa, Hemraj: 1 article (01/2017)
2.	Kaushik, Nutan: 1 article (01/2017)
3.	Ishii, Maki: 1 article (07/2015)
4.	Kadokura, Takayuki: 1 article (07/2015)
5.	Kitajima, Junichi: 1 article (07/2015)
6.	Masuda, Yutaka: 1 article (07/2015)
7.	Takada, Kimihiko: 1 article (07/2015)
8.	Kano, I: 1 article (04/2000)
9.	Nagai, F: 1 article (04/2000)
10.	Satoh, K: 1 article (04/2000)

Related Diseases

1.	Tetraploidy 05/01/1998 - "One of the selected tetraploid lines had about 1.5 times as heavy rhizomes as the diploid and contained atractylodin, hinesol and beta-eudesmol in the rhizome to as great an extent or slightly less than the diploids. "
2.	Stomach Ulcer (Gastric Ulcer) 04/01/2000 - "The effect of So-jutsu as an anti-gastric ulcer agent may be ascribed to the inhibitory effect of hinesol on H+,K+-ATPase activity."
3.	Neoplasms (Cancer) 07/01/2015 - "Therefore, hinesol may represent a novel medicinal drug having indications in the treatment of various cancers, including leukemia. "
4.	Leukemia 07/01/2015 - "Therefore, hinesol may represent a novel medicinal drug having indications in the treatment of various cancers, including leukemia. " 07/01/2015 - "These growth-inhibitory and apoptosis-inducing activities of hinesol in leukemia cells were much stronger than those of β-eudesmol, another compound isolated from the essential oil fraction. " 07/01/2015 - "Hinesol, a compound isolated from the essential oils of Atractylodes lancea rhizome, inhibits cell growth and induces apoptosis in human leukemia HL-60 cells."
5.	Infections 01/01/2017 - "Only 31% of bacterial and 23% of fungal isolates showed their ability in production of Agarospirol by artificial infection method. " 01/01/2017 - "Gas chromatography mass spectroscopy (GC-MS) analysis confirmed development of Agarwood by the presence of Agarospirol compound in samples collected after 3 months of the artificial infection. " 01/01/2017 - "Fungal and Bacterial Diversity Isolated from Aquilaria malaccensis Tree and Soil, Induces Agarospirol Formation within 3 Months after Artificial Infection."

Related Drugs and Biologics

1.	Volatile Oils (Essential Oils)
2.	Adenosine Triphosphatases (ATPase)
3.	atractylodin
4.	beta-eudesmol