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choline transporter

Subscribe to New Research on choline transporter

transporter encoded by the CTR gene; amino acid sequence given in first source

Also Known As:

CHO-1 protein, C elegans; CTL1 protein, rat; HNM1 protein, S cerevisiae; YGL077C protein, S cerevisiae; cudT protein, Staphylococcus xylosus; high-affinity choline transporter; rCTL1 protein, rat

Networked: 35 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins
- Proteins: 90489
  - Carrier Proteins: 11456
    - Membrane Transport Proteins: 165
      - choline transporter: 35
  - Membrane Proteins: 5300
    - Membrane Transport Proteins: 165
      - choline transporter: 35

Experts

1.	Inazu, Masato: 4 articles (11/2014 - 03/2009)
2.	Blakely, Randy D: 4 articles (12/2013 - 12/2009)
3.	Curtis, Brian R: 3 articles (12/2014 - 03/2010)
4.	Aster, Richard H: 3 articles (12/2014 - 03/2010)
5.	Yamada, Tomoko: 3 articles (10/2013 - 03/2009)
6.	Sachs, Ulrich J: 2 articles (07/2015 - 11/2013)
7.	Werth, Silke: 2 articles (07/2015 - 11/2013)
8.	Tjahjono, Yudy: 2 articles (07/2015 - 11/2013)
9.	Bayat, Behnaz: 2 articles (07/2015 - 11/2013)
10.	Santoso, Sentot: 2 articles (07/2015 - 11/2013)

Related Diseases

1.	Pain (Aches) 08/27/2004 - "Intrathecal hemicholinium-3 (HC-3), a reversible inhibitor of choline transporter, did not change the effect of BCh in the tail flick test but produced a non-significant reduction of the effect of BCh against incisional pain. "
2.	Malaria 11/15/2004 - "Thus, the induced permeability pathways in the host erythrocyte membrane and the parasite choline transporter described here form a cooperative transport system that shows great promise for the selective targeting of new agents for the chemotherapy of malaria."
3.	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 04/01/2015 - "Further, our results may shed light on prior association studies linking functional variation within the choline transporter gene and diagnoses of major depression and attention-deficit hyperactivity disorder. " 02/06/2013 - "Functional variation in the gene encoding the presynaptic choline transporter (CHT) has been linked to attention-deficit/hyperactivity disorder. " 12/01/2009 - "Choline transporter gene variation is associated with attention-deficit hyperactivity disorder."
4.	Neuroblastoma 02/01/2011 - "Functional expression of choline transporter-like protein 1 (CTL1) in human neuroblastoma cells and its link to acetylcholine synthesis." 08/01/2009 - "Detection of choline transporter-like 1 protein CTL1 in neuroblastoma x glioma cells and in the CNS, and its role in choline uptake." 08/01/2009 - "The aim of this study was to detect and characterize the choline transporter-like 1 (CTL1/SLC44A1) protein in CNS tissues and the hybrid neuroblastoma x glioma cell line NG108-15, which synthesizes acetylcholine and has high affinity choline transport but does not express the cholinergic high affinity choline transporter 1. The presence of CTL1 protein in NG108-15 cells was confirmed using our antibody G103 which recognizes the C-terminal domain of human CTL1. "
5.	Glioma (Gliomas) 12/01/2013 - "Choline transporters are both expressed on blood-brain barrier (BBB) and glioma, Herein, a choline derivate with high choline transporter affinity was chosen as BBB and glioma dual targeting ligand. " 12/01/2013 - "Choline transporter-targeting and co-delivery system for glioma therapy." 08/01/2009 - "Detection of choline transporter-like 1 protein CTL1 in neuroblastoma x glioma cells and in the CNS, and its role in choline uptake." 08/01/2009 - "The aim of this study was to detect and characterize the choline transporter-like 1 (CTL1/SLC44A1) protein in CNS tissues and the hybrid neuroblastoma x glioma cell line NG108-15, which synthesizes acetylcholine and has high affinity choline transport but does not express the cholinergic high affinity choline transporter 1. The presence of CTL1 protein in NG108-15 cells was confirmed using our antibody G103 which recognizes the C-terminal domain of human CTL1. "

Related Drugs and Biologics

1.	choline transporter
2.	Choline (Choline Chloride)
3.	Acetylcholine (Acetylcholine Chloride)
4.	Antibodies
5.	Proteins (Proteins, Gene)
6.	Choline O-Acetyltransferase (Choline Acetyltransferase)
7.	Antigens
8.	Protein Kinase C-alpha
9.	Vesicular Acetylcholine Transport Proteins (Vesicular Acetylcholine Transporter)
10.	Neurotransmitter Agents (Neurotransmitter)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)