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Androctonus australis AaIT neurotoxin (AaIT)

amino acid sequence has been determined

Also Known As:

AaIT; AaIT neurotoxin, Androctonus australis

Networked: 12 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Complex Mixtures: 1906
- Venoms: 4328
  - Arthropod Venoms: 770
    - Scorpion Venoms: 373
      - Androctonus australis AaIT neurotoxin: 12
Biological Factors: 2472
- Biological Toxins: 20
  - Venoms: 4328
    - Arthropod Venoms: 770
      - Scorpion Venoms: 373
        Androctonus australis AaIT neurotoxin: 12

Experts

1.	Elazar, M: 2 articles (08/2001 - 09/2000)
2.	Zlotkin, E: 2 articles (08/2001 - 09/2000)
3.	Ai, Hui-Sheng: 1 article (01/2021)
4.	Guo, Mei: 1 article (01/2021)
5.	Huang, Hui-Huang: 1 article (01/2021)
6.	Huang, Lei: 1 article (01/2021)
7.	Jiang, Tian-Jun: 1 article (01/2021)
8.	Jiao, Yan-Mei: 1 article (01/2021)
9.	Jin, Lei: 1 article (01/2021)
10.	Li, Yuan-Yuan: 1 article (01/2021)

Related Diseases

1.	Body Weight (Weight, Body) 10/01/1999 - "In the present study the paralytic potency of AaIT to wild type and various mutant strains of houseflies (Musca domestica) and fruitflies (Drosophila melanogaster) was examined and it has been shown that: On the basis of body weight when compared to published data on Sarcophaga falculata blowflies, the Musca and Drosophila flies reveal at least two orders of magnitude decreased susceptibility to the AaIT. " 01/01/1992 - "AaIT induced paralysis of flies within 1-2 h after oral administration, with a lethal dose (LD50) of 10 micrograms/100 mg of body weight. "
2.	Tachycardia (Tachyarrhythmias) 05/01/1995 - "This study reports experience with atrial antitachycardia (AAIT mode) pacing for the management of atrial reentry tachycardia, with emphasis on the risks and benefits of automatic pacing therapy. "
3.	Prostatic Neoplasms (Prostate Cancer) 10/01/2023 - "This study assessed the effectiveness and safety of denosumab (Prolia®) compared to bisphosphonates (alendronate, ibandronate, risedronate, zoledronate), selective estrogen receptor modulators (SERMs) (bazedoxifene, raloxifene) and placebo for the treatment of osteoporosis in hormone-sensitive cancer patients receiving endocrine therapy (men with prostate cancer [MPC] on hormone ablation therapy [HAT], and women with breast cancer [WBC] on adjuvant aromatase inhibitor therapy [AAIT]). "
4.	Osteoporosis 10/01/2023 - "This study assessed the effectiveness and safety of denosumab (Prolia®) compared to bisphosphonates (alendronate, ibandronate, risedronate, zoledronate), selective estrogen receptor modulators (SERMs) (bazedoxifene, raloxifene) and placebo for the treatment of osteoporosis in hormone-sensitive cancer patients receiving endocrine therapy (men with prostate cancer [MPC] on hormone ablation therapy [HAT], and women with breast cancer [WBC] on adjuvant aromatase inhibitor therapy [AAIT]). "
5.	Neoplasms (Cancer) 10/01/2023 - "This study assessed the effectiveness and safety of denosumab (Prolia®) compared to bisphosphonates (alendronate, ibandronate, risedronate, zoledronate), selective estrogen receptor modulators (SERMs) (bazedoxifene, raloxifene) and placebo for the treatment of osteoporosis in hormone-sensitive cancer patients receiving endocrine therapy (men with prostate cancer [MPC] on hormone ablation therapy [HAT], and women with breast cancer [WBC] on adjuvant aromatase inhibitor therapy [AAIT]). "

Related Drugs and Biologics

1.	Aromatase Inhibitors
2.	Raloxifene Hydrochloride (Evista)
3.	Selective Estrogen Receptor Modulators (SERM)
4.	Alendronate (Alendronate Sodium)
5.	Hormones (Hormone)
6.	Diphosphonates (Bisphosphonates)
7.	Ibandronic Acid (Boniva)
8.	Zoledronic Acid (Zometa)
9.	Denosumab
10.	Risedronic Acid (Actonel)

Related Therapies and Procedures

1.	Therapeutics
2.	Oral Administration