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N-butylbenzenesulfonamide (NBBS)

a neurotoxic plasticising agent

Also Known As:

NBBS; N-butylbenzenesulphonamide

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133

Experts

1.	Rider, Cynthia V: 2 articles (05/2020 - 01/2020)
2.	Waidyanatha, Suramya: 2 articles (05/2020 - 01/2020)
3.	Blystone, Chad: 1 article (05/2020)
4.	South, Natalie L: 1 article (05/2020)
5.	Turner, Katie: 1 article (05/2020)
6.	Vallant, Molly: 1 article (05/2020)
7.	Xie, Guanhua: 1 article (05/2020)
8.	Burback, Brian: 1 article (01/2020)
9.	Cao, Yu: 1 article (01/2020)
10.	Gibbs, Seth: 1 article (01/2020)

Related Diseases

1.	Hypersensitivity (Allergy) 01/01/2015 - "The purpose of this study was to evaluate the potential for hypersensitivity and immune suppression following dermal exposure to NBBS using a murine model. "
2.	Body Weight (Weight, Body) 05/11/2020 - "The lowest observed effect level (LOEL) based on significantly lower body weights was 5000 ppm NBBS for F0 dams and 2500 ppm NBBS for F1 pups. " 01/01/2020 - "This work investigates the toxicokinetic behavior of NBBS in rodents following a single gavage (20, 60, and 200 mg/kg body weight) or multi-day feed administration (500, 1000, and 2000 ppm). " 01/01/2015 - "In contrast to body weight, a significant elevation in kidney and liver weight was observed following dermal exposure to all concentrations of NBBS. " 12/01/1995 - "N-butyl benzenesulfonamide (NBBS), one of the sulfonamide plasticizers, induced characteristic effects to Wistar rats after acute repeated exposures (300 mg/kg body weight, ip every 6 h). "
3.	Abnormal Reflex (Hyperreflexia) 01/01/1991 - "Young adult New Zealand white rabbits, inoculated repeatedly with NBBS by the intracisternal or intraperitoneal routes, developed a dose-dependent motor dysfunction characterized by limb splaying, hyperreflexia, hypertonia, gait impairment, and abnormal righting reflexes. "
4.	Prostatitis 12/01/2010 - "Thus, NBBS and its derivatives may serve as novel chemical platform for treatment prostatitis, BPH and PCa."
5.	Prostatic Neoplasms (Prostate Cancer) 12/01/2010 - "NBBS isolated from Pygeum africanum bark exhibits androgen antagonistic activity, inhibits AR nuclear translocation and prostate cancer cell growth."

Related Drugs and Biologics

1.	Sodium Bicarbonate (Baking Soda)
2.	Sulfonamides
3.	Plasticizers
4.	Androgens
5.	Benzenesulfonamides