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ferumoxides (Feridex)

Subscribe to New Research on ferumoxides

colloidal particles of magnetite coated with dextran

Also Known As:

Feridex; AMI 25; AMI25; AquaMag100; Berlex brand of ferumoxides; Endorem; Guerbert brand of ferumoxides; Guerbet brand of ferumoxides; Resovist; SH U 555A; SHU 555A; SHU-555A; WIN 39996; carboxydextran-coated superparamagnetic iron oxide; dextran-coated SPIO; dextran-coated superparamagnetic iron oxide; ferucarbotran

Networked: 212 relevant articles (21 outcomes, 38 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Choi, Dongil: 8 articles (01/2010 - 04/2002)
2.	Lee, Won Jae: 7 articles (01/2010 - 04/2002)
3.	Kim, Seung Hoon: 7 articles (05/2008 - 04/2002)
4.	Frank, Joseph A: 6 articles (04/2011 - 08/2003)
5.	Arbab, Ali S: 6 articles (09/2007 - 10/2002)
6.	Lim, Jae Hoon: 6 articles (09/2006 - 04/2002)
7.	Minamiya, Yoshihiro: 5 articles (08/2015 - 08/2003)
8.	Mori, Kensaku: 5 articles (06/2015 - 10/2002)
9.	Kim, Joo Hee: 5 articles (07/2011 - 05/2002)
10.	Chung, Jae-Joon: 5 articles (07/2011 - 05/2002)

Related Diseases

1.	Hepatocellular Carcinoma (Hepatoma) 01/01/2009 - "Detection of hepatocellular carcinoma by ferucarbotran-enhanced magnetic resonance imaging: the efficacy of accumulation phase fat-suppressed T1-weighted imaging." 09/01/2007 - "To investigate the diagnostic efficacy of sequentially acquired gadobenete dimeglumine-enhanced 3-dimensional dynamic magnetic resonance imaging (MRI) and Resovist-enhanced MRI for detecting hepatocellular carcinoma (HCC) by comparing with combined computed tomography (CT) hepatic arteriography (CTHA) and CT arterioportography (CTAP) using 16-slice multidetector CT. " 04/01/2005 - "Seventy-three consecutive patients with 121 hepatocellular carcinomas underwent ferucarbotran-enhanced MRI, including a dynamic study, and triple-phase MDCT before hepatic resection. " 02/01/2001 - "The purpose of this study was to compare ferumoxides-enhanced MR imaging with combined helical CT during arterial portography and CT hepatic arteriography for preoperative detection of hepatocellular carcinomas. " 11/01/2013 - "101 hepatocellular carcinomas were treated by RFA after ferucarbotran administration. "
2.	Neoplasms (Cancer) 11/01/1995 - "Thus, ENDOREM is useful for preoperative staging of liver tumors due to improvement in lesion detection and delineation of the hepatic vascular system." 05/01/2009 - "The feasibility of magnetic resonance (MR) imaging with impaired clearance of ferucarbotran to visualize ablated liver parenchyma surrounding a tumor (ablative margin [AM]) was evaluated after radiofrequency (RF) ablation of the liver. " 08/01/1995 - "Resovist improved tumor liver contrast and lesion-conspicuity, especially for lesions smaller than 1 cm. The dose of 8 mumol Fe/kg was sufficient to achieve diagnostic tumor-liver contrast. " 10/01/2005 - "This animal study showed that ferucarbotran was useful to detect bone marrow tumors. " 03/01/2000 - "In a clinical study, 10 micromol/kg of ferumoxides was given in 34 consecutive patients with 31 solid tumors. "
3.	Neoplasm Metastasis (Metastasis) 12/01/1998 - "We conclude that ferumoxides-enhanced MR imaging is superior to unenhanced MR imaging and biphasic spiral CT for depiction of colorectal liver metastases. " 12/01/1998 - "The purpose of this study was to compare the efficacy of unenhanced and ferumoxides-enhanced magnetic resonance imaging with that of dual-phase spiral CT and spiral CT during arterial portography (CTAP) for the detection of colorectal liver metastases. " 09/01/2010 - "To retrospectively evaluate the efficacy of biphasic magnetic resonance imaging (MRI) of the liver with ferucarbotran-enhancement for the characterization of hepatic metastases. " 09/01/2010 - "Characterization of liver metastases: the efficacy of biphasic magnetic resonance imaging with ferucarbotran-enhancement." 11/01/2008 - "Combining ferucarbotran-enhanced T2*W-GRE and T2W-TSE has additive efficacy for detecting HCC in cirrhotic patients, but T2W-TSE is preferred for detecting metastases in non-cirrhotic patients."
4.	Fibrosis (Cirrhosis) 10/01/2002 - "Ferumoxides-enhanced gradient-echo sequences improved the diagnostic accuracy and the sensitivity for detecting malignant hepatic lesions in patients with end-stage cirrhosis of the liver. " 09/01/1999 - "The dose-dependency and rate of decay of efficacy of Resovist in cirrhosis were similar to those in normal liver, although the efficacy was less in cirrhotic liver and both the dose-dependency and rate of decay of efficacy were dependent on imaging parameters." 03/01/2001 - "We describe ferumoxides-enhanced magnetic resonance imaging findings in a 60-year-old man with confluent hepatic fibrosis in advanced cirrhosis. " 03/01/2001 - "Confluent hepatic fibrosis in cirrhosis: ferumoxides-enhanced MR imaging findings." 09/01/2003 - "Forty-two liver transplant candidates with end-stage cirrhosis underwent SPIO-enhanced MRI at 1.5T, using either 15 micromol/kg or 7.5 micromol/kg ferumoxides. "
5.	Liver Cirrhosis (Hepatic Cirrhosis) 07/01/2012 - "Capturing the signal dynamics during bolus injection of ferucarbotran in DC-MRI of the liver allows for semiquantitative assessment of hepatic perfusion that may be helpful for a more precise characterisation of liver cirrhosis and focal liver lesions." 09/01/2003 - "The aim of this study was to establish whether enhancement of the liver by the MRI contrast agent ferumoxides could be effectively achieved at a reduced dose of 7.5 micromol/kg in patients with advanced liver cirrhosis. " 01/01/2000 - "The goal of this study was compare the effect of Endorem on the signal intensity of the spleen in patients with normal liver tissue and in patients with liver cirrhosis. " 07/01/2012 - "In total 31 patients (21 men; 58 ± 10 years) including 18 patients with biopsy proven liver cirrhosis prospectively underwent clinically indicated DC-MRI at 1.5 Tesla (T) with dynamic T2-weighted gradient-echo imaging after ferucarbotran bolus injection. " 05/01/2002 - "Effect of resovist on rats with different severities of liver cirrhosis."

Related Drugs and Biologics

1.	Gadolinium
2.	ferric oxide (iron oxide)
3.	Gadolinium DTPA (Magnevist)
4.	N,N'- bis(pyridoxal- 5- phosphate)ethylenediamine- N,N'- diacetic acid (mangafodipir)
5.	Doxorubicin (Adriamycin)
6.	ferumoxides (Feridex)
7.	Iron
8.	Protamines (Protamine Sulfate)
9.	Protons (Proton)
10.	TES

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Lymph Node Excision (Lymph Node Dissection)
3.	Heterologous Transplantation (Xenotransplantation)
4.	Transplantation (Transplant Recipients)
5.	Transplants (Transplant)