cytomegalovirus matrix protein 65kDa

encoded by UL83 gene; amino acid sequence has been determined; a common infectious complication in renal transplant recipients

Also Known As:

CMV pp65 antigen; HCMV matrix protein gp65, Human herpesvirus 5; UL83 protein, Cytomegalovirus; UL83 protein, Human herpesvirus 5; cytomegalovirus phosphoprotein 65; matrix protein 65kDa, Human herpesvirus 5; matrix protein, cytomegalovirus pp65; pp65 protein, Cytomegalovirus; ppUL83 protein, Cytomegalovirus

Networked: 23 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Viral Proteins: 4250
    - Viral Structural Proteins: 171
      - Viral Envelope Proteins: 291
        Viral Matrix Proteins: 23
        cytomegalovirus matrix protein 65kDa: 23

Experts

1.	Jung, Keunok: 1 article (01/2022)
2.	Kim, Chul-Ho: 1 article (01/2022)
3.	Kim, Jeong-Ah: 1 article (01/2022)
4.	Kim, Yong-Sung: 1 article (01/2022)
5.	Ko, Deok-Han: 1 article (01/2022)
6.	Lee, Se-Young: 1 article (01/2022)
7.	Son, Min-Jeong: 1 article (01/2022)
8.	Yoo, Sojung: 1 article (01/2022)
9.	Chen, Lichun: 1 article (10/2020)
10.	Chen, Qingshan: 1 article (10/2020)

Related Diseases

1.	Infections 10/01/2020 - "The results of immunofluorescence showed that a large number of fluorescent green of CMV pp65 antigen signals appeared in the cytoplasm of CMV infection group. " 01/01/2005 - "To evaluate the clinical significance of flow cytometry (FCM) to detect the cytomegalovirus (CMV) PP65 antigen in patients with CMV infection. " 10/27/2000 - "The patients were followed prospectively for 3 months with serial measurements of CMV pp65 antigen for monitoring activity of CMV infections. " 01/01/1999 - "Immunostaining of the cytomegalovirus (CMV) pp65 antigen in the nucleus of peripheral blood leukocytes is a highly specific tool for diagnosis of active CMV infection. " 01/01/1993 - "We conclude that (1) insufficient results obtained with the CMV antigenemia assay by other investigators are mainly due to technical problems that can easily be overcome by the protocol presented and (2) the detection of CMV pp65 antigen in peripheral blood leukocytes is an excellent tool for rapid and early diagnosis of CMV infection."
2.	Acquired Immunodeficiency Syndrome (AIDS) 10/01/2008 - "In HIV/AIDS patients with CD(4)(+)T cell count </= 100 cells/microl, routine check for CMV pp65 antigen, specific anti-CMV IgM and ophthalmofundoscopy are recommended. " 01/01/1996 - "The virological response to antiviral treatment of cytomegalovirus (CMV) infection in patients with AIDS can be monitored by the identification and quantification of CMV pp65 antigen in blood polymorphonuclear leukocyte cells (PMNL). " 08/01/2004 - "3 cases of CMV retinitis were acquired immune deficiency syndrome patients with CD4+ T cell count less than 50/ microl; 2 patients developed multiple organ failure; (3) The positive rates of CMV pp65 antigen and specific IgM assays were 85.3% and 68.3%, respectively; (4) Comparing with normal controls, all patients with CMV disease had decreased B cell and nature killer cells, increased CD8+ T cell percentage and a reversed CD4+/CD8+ ratio; further more, the patients with underlying diseases had lower CD4+ T-cell and CD8+ T-cell counts than those without underlying diseases. "
3.	Retinitis 11/15/1997 - "CMV retinitis and CMV antigenemia assay (CMV-Ag: numbers of polymorphonuclear leukocytes positive for CMV pp65 antigen per 1.5 x 10(5) cells) are the least invasive and easily accessible examinations to assess the CMV disease activity. " 08/01/2004 - "3 cases of CMV retinitis were acquired immune deficiency syndrome patients with CD4+ T cell count less than 50/ microl; 2 patients developed multiple organ failure; (3) The positive rates of CMV pp65 antigen and specific IgM assays were 85.3% and 68.3%, respectively; (4) Comparing with normal controls, all patients with CMV disease had decreased B cell and nature killer cells, increased CD8+ T cell percentage and a reversed CD4+/CD8+ ratio; further more, the patients with underlying diseases had lower CD4+ T-cell and CD8+ T-cell counts than those without underlying diseases. "
4.	Atherosclerosis 01/01/2016 - "Positive Expression of Human Cytomegalovirus Phosphoprotein 65 in Atherosclerosis."
5.	Squamous Cell Neoplasms (Squamous Cell Cancer) 11/01/2017 - "We have investigated the direct actions of these drugs on CTL functions in in vitro experiments using cytomegalovirus (CMV) pp65 antigen-specific CTLs (CMVpp65-CTLs) and oral squamous cell cancer (OSCC) cell lines overexpressing CMVpp65 antigen as target cells. "

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2.	Immunoglobulin M (IgM)
3.	DNA (Deoxyribonucleic Acid)
4.	Antiviral Agents (Antivirals)
5.	Antigens
6.	Vaccines
7.	RNA (Ribonucleic Acid)
8.	Peptides (Polypeptides)
9.	Indicators and Reagents (Reagents)
10.	Monoclonal Antibodies