Quinidine FDA Link Generic

An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.

Also Known As:

Chinidin; Quinidex; Quinora; Adaquin; Apo-Quinidine; Quincardine; Quinidine Sulfate; Apo Quinidine; Sulfate, Quinidine; Cinchonan-9-ol, 6'-methoxy-, (9S)-

Pharmalogical Action Categories:

Adrenergic alpha-Antagonists
Anti-Arrhythmia Agents
Antimalarials
Cytochrome P-450 CYP2D6 Inhibitors
Enzyme Inhibitors
Muscarinic Antagonists
Voltage-Gated Sodium Channel Blockers

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Cinchona Alkaloids: 29
    - Quinidine: 1737
- Bridged-Ring Heterocyclic Compounds
  - Quinuclidines: 20
    - Quinidine: 1737
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Quinidine: 1737

10,11-dihydroxydihydroquinidine N-oxide

Bio-Agent Context: Research Results