phlorofucofuroeckol A

phlorotannin from Ecklonia kurome; structure given in first source

Also Known As:

1,11-di-(3,5-dihydroxyphenoxy)benzofuro(3,2-a)dibenzo(b,e)(1,4)-dioxin-2,4,8,10,14-pentaol; phlorofucofuroeckol-A; Benzo(b)benzofuro(3,2-f)(1,4)benzodioxin-1,3,6,10,12-pentol, 4,9-bis(3,5-dihydroxyphenoxy)-

Networked: 9 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Shin, Hyeon-Cheol: 2 articles (08/2021 - 04/2015)
2.	Kim, Hyeung-Rak: 2 articles (07/2019 - 04/2013)
3.	Kwon, Tae-Hyung: 2 articles (03/2016 - 07/2015)
4.	Park, Nyun-Ho: 2 articles (03/2016 - 07/2015)
5.	Han, Seung-Hee: 1 article (08/2021)
6.	Kim, Byeong-Gon: 1 article (08/2021)
7.	Kim, Min-Kyung: 1 article (08/2021)
8.	Lee, Jun-Ho: 1 article (08/2021)
9.	Oh, Seung-Ha: 1 article (08/2021)
10.	Park, Moo-Kyun: 1 article (08/2021)

Related Diseases

1.	Alzheimer Disease (Alzheimer's Disease) 04/01/2015 - "For butyrylcholinesterase, a new target for the treatment of Alzheimer's disease, phlorofucofuroeckol-A (PFF-A), showed a particularly potent inhibitory activity (IC50 0.95 μM), which is over 100-fold greater than for acetylcholinesterase. " 01/01/2023 - "In mouse models of Alzheimer's disease, ethanol intoxication and fear stress, the phlorotannin monomer phloroglucinol and the compounds eckol, dieckol and phlorofucofuroeckol A have been shown to improve cognitive function. "
2.	Hyperglycemia 04/05/2015 - "Phlorofucofuroeckol A isolated from Ecklonia cava alleviates postprandial hyperglycemia in diabetic mice." 04/05/2015 - "This study was designed to investigate whether phlorofucofuroeckol A inhibited α-glucosidase and α-amylase activities and alleviated postprandial hyperglycemia in diabetic mice. " 04/05/2015 - "These results suggested that phlorofucofuroeckol A is a potent α-glucosidase inhibitor and can alleviate the postprandial hyperglycemia that is caused by starch. "
3.	Neurodegenerative Diseases (Neurodegenerative Disease) 04/01/2013 - "These findings suggest that phlorofucofuroeckol A can be considered as a nutraceutical candidate for the treatment of neuroinflammation in neurodegenerative diseases."
4.	Colorectal Neoplasms (Colorectal Cancer) 03/29/2016 - "In Vitro Anticancer Activity of Phlorofucofuroeckol A via Upregulation of Activating Transcription Factor 3 against Human Colorectal Cancer Cells."
5.	Obesity 07/01/2015 - "We investigated the anti-obesity effects of 6,6'-bieckol, 6,8'-bieckol, 8,8'-bieckol, dieckol and phlorofucofuroeckol A isolated from E. "

Related Drugs and Biologics

1.	dieckol
2.	eckol
3.	Phloroglucinol
4.	Ethanol (Ethyl Alcohol)
5.	Glucosidases
6.	Amylases
7.	Activating Transcription Factor 3
8.	Monophenol Monooxygenase (Tyrosinase)
9.	Starch (Cornstarch)
10.	Proteins (Proteins, Gene)