ganglioside GD1alpha (GD1alpha)

05/15/1997 - "Ganglioside GD1alpha functions in the adhesion of metastatic tumor cells to endothelial cells of the target tissue."
05/15/1997 - "GD1alpha and GM1b inhibited the adhesion when HSE cells were incubated prior to coculture with the tumor cells. "
05/15/1997 - "On the basis of the results of glycosphingolipid analysis, we investigated the functional role of GD1alpha in H10 cells in the adhesion of the tumor cells to the target tissue by using hepatic sinusoidal endothelial (HSE) cells. "
12/11/1998 - "GD1alpha-replica peptides functionally mimic GD1alpha, an adhesion molecule of metastatic tumor cells, and suppress the tumor metastasis."
01/28/2000 - "Suppression of GD1alpha ganglioside-mediated tumor metastasis by liposomalized WHW-peptide."

05/15/1997 - "These data indicate that GD1alpha functions as an adhesion molecule in the process of metastasis of H10 cells."
12/11/1998 - "GD1alpha-replica peptides functionally mimic GD1alpha, an adhesion molecule of metastatic tumor cells, and suppress the tumor metastasis."
12/11/1998 - "These results indicate that GD1alpha plays an important role for metastasis of RAW117-H10 cells, and the peptides obtained by the present procedure are able to mimic the functional role of the glycoconjugate."
01/28/2000 - "Suppression of GD1alpha ganglioside-mediated tumor metastasis by liposomalized WHW-peptide."

06/01/1999 - "Eleven patients with Guillain-Barré syndrome had remarkably high IgG anti-GD1alpha antibody titers, but no GD1alpha was detected in human peripheral nerve. "
06/01/1999 - "Antibodies to GD1alpha and to GQ1beta in Guillain-Barré syndrome and the related disorders."
06/01/1999 - "GD1alpha may induce the production of IgG anti-GD1alpha antibody which cross-reacts with GD1a or GM1b, and subsequently functions in the development of Guillain-Barré syndrome. "

10/22/1999 - "It is concluded that this enzyme is involved in the synthesis of GD1alpha in the nervous tissues, and the CAG repeats may have implications in neurodegenerative diseases."

01/28/2000 - "GD1alpha ganglioside-replica peptides were recently isolated from a phage-displayed random pentadecapeptide library by assaying for inhibition of adhesion of RAW117-H10 lymphosarcoma cells to hepatic sinusoidal microvessel endothelial (HSE) cells. "