factor XIII subunit A

causes congenital deficiency of factor XIII

Networked: 12 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzyme Precursors: 724
  - Factor XIII: 1043
    - factor XIII subunit A: 12
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Blood Coagulation Factors: 5376
      - Factor XIII: 1043
        factor XIII subunit A: 12
  - Protein Precursors: 37
    - Enzyme Precursors: 724
      - Factor XIII: 1043
        factor XIII subunit A: 12
Biological Factors: 2472
- Blood Coagulation Factors: 5376
  - Factor XIII: 1043
    - factor XIII subunit A: 12

Experts

1.	Rosendaal, F R: 2 articles (12/2007 - 11/2001)
2.	Katona, Eva: 2 articles (01/2007 - 08/2005)
3.	Muszbek, László: 2 articles (01/2007 - 08/2005)
4.	Deng, Mingyang: 1 article (01/2021)
5.	Hu, Chunhong: 1 article (01/2021)
6.	Li, Bin: 1 article (01/2021)
7.	Li, Ji: 1 article (01/2021)
8.	Luo, Yujiao: 1 article (01/2021)
9.	Yan, Wenzhe: 1 article (01/2021)
10.	Zhang, Guangsen: 1 article (01/2021)

Related Diseases

1.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 08/01/2005 - "This study was designed to study the sensitivity and specificity of factor XIII subunit A (FXIII-A) labelling in cultured myeloblastic and monoblastic cell lines and to investigate the intracytoplasmic expression of FXIII-A in de novo acute myeloid leukemia (AML) samples. "
2.	Neoplasms (Cancer) 08/01/2014 - "Factor XIII subunit A (FXIII-A) is used as a diagnostic marker in a wide range of dermatological diseases ranging from inflammatory lesions to malignancies, although neither the cell types responsible for its expression nor the mechanism(s) resulting in its local accumulation in pathological conditions have been characterized. " 01/01/2021 - "The expression of coagulant factor XIII subunit A (FXIII-A) is significantly increased in some types of cancer cells and tumor-associated macrophages (TAMs). " 01/01/2020 - "Whole exome sequencing revealed a rare shared heterozygous missense variant in the F13A1 gene encoding factor XIII subunit A (FXIII-A), a transglutaminase involved in hemostasis, wound healing, tumor growth, and apoptosis. " 11/01/1998 - "Double and treble labelings were used to detect fibrinogen and fibrin in combination with marker antigens for tumor cells (cytokeratin), endothelial cells (von Willebrand factor), macrophages (recognized by KiM7), as well as factor XIII subunit A (FXIIIA) and tenascin (an embryonic extracellular matrix protein newly expressed during tumorigenesis). "
3.	Factor XIII Deficiency 06/01/1997 - "Factor XIII deficiency due to a Leu660Pro mutation in the factor XIII subunit-a gene in three unrelated Palestinian Arab families." 02/01/2015 - "To investigate the mechanisms of DelCD11-279 of factor XIII subunit A mRNA in the pathogenesis of hereditary factor XIII deficiency. "
4.	Vascular Remodeling 11/01/2001 - "We assessed the potential role of 3 factor XIII subunit A coding-sequence polymorphisms, along with a promoter polymorphism of plasminogen activator inhibitor-1 (PAI-1, which is also involved in fibrin stabilization and vascular remodeling), in young white women with hemorrhagic stroke. "
5.	Carcinogenesis 11/01/1998 - "Double and treble labelings were used to detect fibrinogen and fibrin in combination with marker antigens for tumor cells (cytokeratin), endothelial cells (von Willebrand factor), macrophages (recognized by KiM7), as well as factor XIII subunit A (FXIIIA) and tenascin (an embryonic extracellular matrix protein newly expressed during tumorigenesis). "

Related Drugs and Biologics

1.	Fibrinogen (Factor I)
2.	Fibrin
3.	Apolipoprotein E2
4.	Tenascin
5.	Plasminogen Activator Inhibitor 1
6.	Extracellular Matrix Proteins
7.	von Willebrand Factor
8.	Messenger RNA (mRNA)
9.	Transglutaminases
10.	Plasminogen Activators (Plasminogen Activator)