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isochorismatase

catalyzes the conversion of isochorismate & water to 2,3-dihydroxy-2,3-dihydrobenzoate & pyruvate

Also Known As:

2,3-dihydro-2,3-dihydroxybenzoate synthetase

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - isochorismatase: 7

Experts

1.	Chen, Xiang-Ling: 1 article (01/2022)
2.	Gao, Xiao-Qiang: 1 article (01/2022)
3.	Lu, Yin-Ying: 1 article (01/2022)
4.	Xiang, Jiao: 1 article (01/2022)
5.	Cardona, Andrés F: 1 article (03/2021)
6.	Danese, Elisa: 1 article (03/2021)
7.	Hong, Xuan: 1 article (03/2021)
8.	Jiang, Gening: 1 article (03/2021)
9.	Jiang, Yan: 1 article (03/2021)
10.	Malhotra, Jyoti: 1 article (03/2021)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2022 - "Isochorismatase domain-containing 1 (ISOC1) plays a carcinogenic role in various tumors. " 10/01/2011 - "One of these non-HDAC targets, isochorismatase domain-containing protein 2 (ISOC2) is putative hydrolase associated with the negative regulation of the tumor-suppressor p16(INK4a). "
2.	Stomach Neoplasms (Stomach Cancer) 11/01/2020 - "To explore the role and potential mechanism of isochorismatase domain-containing 1 (ISOC1) in gastric cancer. "
3.	Lung Neoplasms (Lung Cancer) 03/01/2021 - "Isochorismatase domain-containing protein 1 (ISOC1) participates in DNA damage repair and inflammation-related pathways to promote lung cancer development." 03/01/2021 - "Isochorismatase domain-containing protein 1 (ISOC1) has been reported as a potential biomarker in gastrointestinal cancer, while its function in lung cancer has not been determined. "
4.	Inflammation (Inflammations) 03/01/2021 - "Isochorismatase domain-containing protein 1 (ISOC1) participates in DNA damage repair and inflammation-related pathways to promote lung cancer development."
5.	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 03/01/2021 - "Isochorismatase domain-containing protein 1 (ISOC1) has been reported as a potential biomarker in gastrointestinal cancer, while its function in lung cancer has not been determined. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Cyclin-Dependent Kinase Inhibitor p16
3.	Biomarkers (Surrogate Marker)
4.	Hydrolases
5.	Estrogens (Estrogen)
6.	isochorismate synthase