norbergenin

bergenin derivative isolated from the root of Ardisia crenata

Also Known As:

Pyrano(3,2-c)(2)benzopyran-6(2H)-one, 3,4,4a,10b-tetrahydro-3,4,8,9,10-pentahydroxy-2-(hydroxymethyl)-, (2R-(2alpha,3beta,4alpha,4aalpha,10bbeta))-

Networked: 3 relevant articles (1 outcomes, 1 trials/studies)

1.	Stomach Ulcer (Gastric Ulcer) 10/01/1997 - "Oral administration of bergenin and norbergenin, two isocoumarins, isolated from the leaves and roots of Flueggea microcarpa and luvangetin, a pyranocoumarin isolated from the seeds of Aegle marmelos Correa, showed significant protection against pylorus-ligated and aspirin-induced gastric ulcers in rats and cold restraint stress-induced gastric ulcers in rats and guinea pigs. "
2.	Arthritis (Polyarthritis) 06/13/2007 - "Immunomodulatory effect of bergenin and norbergenin against adjuvant-induced arthritis--a flow cytometric study."
3.	Peptic Ulcer (Peptic Ulcers) 09/01/2003 - "From these results, it is presumed that bergenin and norbergenin may be the active components of Mallotus japonicus in inhibiting TH, and these inhibitory effects may be partially responsible for the clinical use of Mallotus japonicus in treating peptic ulcer by reducing the availability of dopa/dopamine in vivo."

1.	bergenin
2.	Isocoumarins
3.	Aspirin (Acetylsalicylic Acid)
4.	Dopamine (Intropin)
5.	Dihydroxyphenylalanine (Dopa)

1.	Oral Administration