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ZK 95962

inhibits photosensitive seizures in man; a selective benzodiazepine receptor agonist; structure given in first source

Also Known As:

ZK-95962

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Carbolines: 283
      - ZK 95962: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Indole Alkaloids: 200
        Carbolines: 283
        ZK 95962: 2
  - 3-Ring Heterocyclic Compounds
    - Carbolines: 283
      - ZK 95962: 2

Related Diseases

1.	Generalized Epilepsy 03/01/1990 - "A single-dose study of the beta-carboline, ZK 95962, on photosensitive generalized paroxysmal activity in the EEG was conducted in 6 patients with primary generalized epilepsy. "
2.	Seizures (Absence Seizure) 03/01/1990 - "Inhibition of photosensitive seizures in man by the beta-carboline, ZK 95962, a selective benzodiazepine receptor agonist." 09/01/1987 - "Derivatives of ethyl-beta-carboline-3-carboxylate, ZK 91296, ZK 93423 and ZK 95962 have potent anticonvulsant activity against sound-induced seizures in audiogenic DBA/2 mice and against photically-induced seizures in the baboon, Papio papio. "
3.	Myoclonus (Nocturnal Myoclonus) 03/01/1990 - "The feelings of uneasiness and myoclonic jerks, provoked by photostimulation, were also abolished by ZK 95962, but not by placebo injections. "
4.	Body Weight (Weight, Body) 03/01/1990 - "A double-blind cross-over study with 2 injections of ZK 95962 (20 micrograms/kg body weight repeated 10 min after 1st injection) and 2 placebo injections were carried out in a randomized order, with 4 h intervals between the injections with active drug and placebo. "

Related Drugs and Biologics

1.	norharman
2.	GABA-A Receptors (GABA(A) Receptor)
3.	Anticonvulsants (Antiepileptic Drugs)
4.	ZK 93423
5.	ZK 91296
6.	beta-carboline-3-carboxylic acid ethyl ester

Related Therapies and Procedures

1.	Injections