HLA-DQ6 antigen

Also Known As:

HLA DQ6; HLA DQw6; HLA-DQ6; HLA-DQw6; HLA-DQw6 antigen

Networked: 36 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class II: 2170
        HLA-D Antigens: 238
        HLA-DQ Antigens: 880
        HLA-DQ6 antigen: 36
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class II: 2170
        HLA-D Antigens: 238
        HLA-DQ Antigens: 880
        HLA-DQ6 antigen: 36
  - Membrane Proteins: 10078
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class II: 2170
        HLA-D Antigens: 238
        HLA-DQ Antigens: 880
        HLA-DQ6 antigen: 36
Biological Factors: 2472
- Antigens: 143924
  - Surface Antigens: 5813
    - Histocompatibility Antigens: 1132
      - HLA Antigens: 8934
        HLA-D Antigens: 238
        HLA-DQ Antigens: 880
        HLA-DQ6 antigen: 36
      - Histocompatibility Antigens Class II: 2170
        HLA-D Antigens: 238
        HLA-DQ Antigens: 880
        HLA-DQ6 antigen: 36
  - Isoantigens: 1221
    - Histocompatibility Antigens: 1132
      - HLA Antigens: 8934
        HLA-D Antigens: 238
        HLA-DQ Antigens: 880
        HLA-DQ6 antigen: 36
      - Histocompatibility Antigens Class II: 2170
        HLA-D Antigens: 238
        HLA-DQ Antigens: 880
        HLA-DQ6 antigen: 36

Experts

1.	David, C S: 3 articles (11/2001 - 03/2000)
2.	David, Chella S: 2 articles (01/2014 - 01/2002)
3.	Dillner, J: 2 articles (10/2001 - 10/2000)
4.	Ghaderi, M: 2 articles (10/2001 - 10/2000)
5.	Hallmans, G: 2 articles (10/2001 - 10/2000)
6.	Lenner, P: 2 articles (10/2001 - 10/2000)
7.	Sanjeevi, C B: 2 articles (10/2001 - 10/2000)
8.	Wiklund, F: 2 articles (10/2001 - 10/2000)
9.	Alves, Rui: 1 article (01/2022)
10.	Andeen, Nicole K: 1 article (01/2022)

Related Diseases

1.	Infections 10/01/2000 - "Our study suggests that the TNFa-11 allele is associated with HPV16 infection and associated with CIN in combination with HLA-DQ6 but not by itself." 10/01/2001 - "TNFa-11 was not associated with susceptibility to HPV16 infection, but it increased the risk for cervical cancer with the HLA DQ6 (DQA 10102-DQB 10602) haplotype. " 01/01/2014 - "In contrast, mice expressing HLA-DR4 (DR0402), HLA-DQ6 (DQ0601), HLA-DQ8 (DQ0302), or HLA-DR3 (DR0301) molecules in an EA(0) background were able to elicit specific antibodies and self-cure the infection. "
2.	Hemolysis 11/01/1996 - "The frequency of HLA-DQ6 was higher in asymptomatic DAT-positive blood donors (n = 8, 38% DQ6 positive, p = 0.48) than in DAT-positive hospital and clinic patients (n = 23, 13% DQ6 positive, corrected p value = 0.030, relative risk = 0.13, 95% Cl = 0.04-0.41), 96 percent of whom had evidence of clinical hemolysis. " 11/01/1996 - "This study demonstrates that HLA-DQ6 may have a negative association with a positive DAT result in patients with evidence for hemolysis, and may be a resistance antigen for clinically relevant red cell autoantibodies."
3.	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 07/01/1997 - "Analysis of critical residues of HLA-DQ6 molecules in insulin-dependent diabetes mellitus." 01/01/2019 - "Epitope Stealing as a Mechanism of Dominant Protection by HLA-DQ6 in Type 1 Diabetes." 11/01/1997 - "HLA DQ8 (DQ A10301/DQB10302) molecule is implicated in the susceptibility to insulin dependent diabetes mellitus whereas, HLA DQ6 (DQ A10103/DQB10601) molecule may have a protective effect. "
4.	Asthma (Bronchial Asthma) 01/01/2020 - "HLA DR11 and DQ2 markers could be potential markers of susceptibility to asthma, while HLA-DQ6 may have a protective effect." 10/15/2001 - "To determine the role and contribution of specific HLA class II in the pathogenesis of allergic airway inflammation in cockroach-induced asthma, we generated double-transgenic, double-knockout mice expressing human HLA-DQ8, HLA-DQ6, and CD4 molecules in the absence of mouse class II and mouse CD4. " 01/15/2002 - "To investigate the role of HLA-DQ molecules and/or CD4(+) T cells in the pathogenesis of allergic asthma, we generated HLA-DQ6 and HLA-DQ8 transgenic mice lacking endogenous class II (Abeta(null)) and CD4 genes and challenged them intranasally with short ragweed allergenic extract (SRW). "
5.	Disease Progression 08/01/2001 - "The DR3,DQ2 heterozygous genotype is associated with a more rapid progression of PSC, whereas HLA-DQ6 is associated with a retarded disease progression. " 01/01/2021 - "Although anti-gliadin antibody (AGA) and anti-tissue transglutaminase antibody (ATTGA) were serologically negative, and HLA typing was HLA-DQ6, the patient was ultimately diagnosed as having celiac disease based on the characteristic pathological findings and clinical course. "

Related Drugs and Biologics

1.	Autoantibodies
2.	Antigens
3.	HLA-DQ8 antigen
4.	Peptides (Polypeptides)
5.	HLA Antigens (Human Leukocyte Antigens)
6.	HLA-DR3 Antigen (HLA DR3 Antigen)
7.	Cholinergic Receptors
8.	HLA-DQ Antigens (HLA-DQ)
9.	HLA-DR15 antigen
10.	Cytochromes c (Cytochrome c)