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sulfenosine

structure given in first source

Also Known As:

2-amino-9-beta-D-ribofuranosylpurine-6-sulfenamide; 9H-Purine-6-sulfenamide, 2-amino-9-beta-D-ribofuranosyl-

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleosides: 360
        sulfenosine: 2
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Purine Nucleosides: 360
    - sulfenosine: 2

Related Diseases

1.	Experimental Leukemia 04/09/1990 - "Oxidation of 2-amino-9-beta-D-ribofuranosylpurine-6-sulfenamide to the corresponding 6-sulfonamide facilitates changes in biologic characterization that include activity against thiopurine-refractory experimental leukemia." 04/09/1990 - "Strikingly, the addition of a fully oxidized sulfur atom at the 6 position of sulfenosine produced a purine derivative (sulfonosine) that was remarkably active against experimental leukemia resistant to treatment with either sulfenosine or 6TGR. "
2.	Leukemia L1210 01/01/1990 - "Sulfenosine (8b) at 22 mg/kg per day X 1 showed a T/C of 170, whereas sulfinosine (9b) at 173 mg/kg per day X 1 showed a T/C of 167 against L1210 leukemia. "

Related Drugs and Biologics

1.	Sulfur
2.	2-mercaptopurine
3.	sulfinosine
4.	sulfonosine
5.	purine