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romazarit
Also Known As:
2-((2-(4-chlorophenyl)-4-methyl-5-oxazolyl)methoxy)-2-methylpropionic acid; Ro 31-3948; Ro-31-3948
Networked:
4
relevant articles (
0
outcomes,
2
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Oxazoles: 89
romazarit: 4
Related Diseases
1.
Rheumatoid Arthritis
03/01/1995 - "
1. The response to romazarit, a disease modifying anti-rheumatoid agent, was observed in patients with rheumatoid arthritis (RA) in a double-blind placebo controlled study.
"
03/01/1992 - "
A pharmacokinetic and tolerance study of romazarit in patients with rheumatoid arthritis.
"
03/01/1992 - "
Romazarit is a new drug for which animal pharmacology suggests a disease-modifying action in rheumatoid arthritis (RA).
"
2.
Inflammation (Inflammations)
03/01/1990 - "
In a 5-day adjuvant arthritis model, romazarit inhibited the development of hindpaw inflammation with a minimum effective dose of 30 mg kg-1.
"
03/01/1990 - "
Romazarit showed little or no activity in models of acute inflammation such as rabbit skin edema, carrageenan pleurisy or UV-induced erythema.
"
02/01/1991 - "
In contrast to NSAIDs, romazarit was inactive in animal models of acute inflammation, and furthermore it did not inhibit the cyclooxygenase enzyme in vitro or in vivo.
"
3.
Pleurisy (Pleuritis)
03/01/1990 - "
Romazarit showed little or no activity in models of acute inflammation such as rabbit skin edema, carrageenan pleurisy or UV-induced erythema.
"
4.
Erythema
03/01/1990 - "
Romazarit showed little or no activity in models of acute inflammation such as rabbit skin edema, carrageenan pleurisy or UV-induced erythema.
"
5.
Edema (Dropsy)
03/01/1990 - "
Romazarit showed little or no activity in models of acute inflammation such as rabbit skin edema, carrageenan pleurisy or UV-induced erythema.
"
Related Drugs and Biologics
1.
Collagenases (Collagenase)
2.
Dinoprostone (PGE2)
3.
Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)
4.
Enzymes
5.
Carrageenan
6.
Non-Steroidal Anti-Inflammatory Agents (NSAIDs)