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doxorubicin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer
structure given in first source; micelle-forming polymeric drug
Also Known As:
ADR-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer; PEG-P(Asp(ADR)); adriamycin-conjugated polyethyleneglycol-polyaspartate copolymer
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Naphthacenes
Anthracyclines: 9423
Daunorubicin: 2641
Doxorubicin: 35390
doxorubicin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer: 1
Alcohols: 595
Glycols: 38
Ethylene Glycols: 8
Polyethylene Glycols: 3865
doxorubicin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer: 1
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Naphthacenes
Anthracyclines: 9423
Daunorubicin: 2641
Doxorubicin: 35390
doxorubicin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer: 1
Carbohydrates: 22023
Glycosides: 2119
Aminoglycosides: 5131
Anthracyclines: 9423
Daunorubicin: 2641
Doxorubicin: 35390
doxorubicin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer: 1
Amino Acids, Peptides, and Proteins: 1
Peptides: 82426
doxorubicin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer: 1
Macromolecular Substances: 97
Polymers: 13051
Polyethylene Glycols: 3865
doxorubicin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer: 1
Biomedical and Dental Materials
Polymers: 13051
Polyethylene Glycols: 3865
doxorubicin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer: 1
Technology, Industry, and Agriculture
Manufactured Materials
Biomedical and Dental Materials
Polymers: 13051
Polyethylene Glycols: 3865
doxorubicin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer: 1
Related Diseases
1.
Neoplasms (Cancer)
06/15/1991 - "
Especially against C 26, PEG-P[Asp(ADR)] expressed critical suppression of tumor growth and considerably prolonged life span of the treated mice.
"
06/15/1991 - "
PEG-P[Asp(ADR)] was revealed to express higher antitumor activity than ADR against all the examined tumors except MKN-45.
"
06/15/1991 - "
Toxicity and in vivo antitumor activity against five solid tumors (C 26, C 38, M 5076, MKN-45, MX-1) of Adriamycin (ADR)-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer (PEG-P[Asp(ADR)]) were evaluated, and its pharmacokinetic behavior in blood and biodistribution by i.v. injection were obtained.
"
Related Drugs and Biologics
1.
doxorubicin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer
2.
Doxorubicin (Adriamycin)