Ginkgo biloba extract 761 (Rokan)

extract from Ginkgo leaves in which terpene trilactones (ginkgolides) are enriched to 6% and allergenic ginkgolic acids removed down to a few ppm; used in treatment of peripheral vascular disease & cerebral insufficiency; is an ingredient of Ginkor

Also Known As:

Networked: 395 relevant articles (83 outcomes, 125 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Christen, Yves: 12 articles (01/2009 - 09/2002)
2.	Drieu, K: 10 articles (06/2003 - 01/2000)
3.	Luo, Yuan: 9 articles (01/2009 - 09/2002)
4.	Koh, Phil-Ok: 7 articles (09/2012 - 01/2009)
5.	Hoerr, R: 6 articles (03/2009 - 01/2002)
6.	Drieu, Katy: 6 articles (01/2006 - 09/2002)
7.	Shi, Chun: 5 articles (01/2010 - 02/2009)
8.	Yew, David T: 5 articles (01/2010 - 02/2009)
9.	Domoráková, Iveta: 5 articles (09/2009 - 01/2002)
10.	Mechírová, Eva: 5 articles (09/2009 - 01/2002)

Related Diseases

1.	Dementia (Dementias) 01/01/1995 - "Recent studies in which EGb 761 demonstrated therapeutic effects in the treatment of dementia have earned EGb the approval of the German BGA (Bundesgesundheit Amt) for use in the treatment of dementia." 01/01/2015 - "These findings have been observed in EGb 761 as well and have led to clinical investigation into its use as a therapeutic for conditions such as cognition, dementia, cardiovascular, and cerebrovascular diseases. " 09/01/2015 - "Ginkgo biloba (EGb 761): A Proprietary Leaf Extract of Ginkgo biloba Is Found to be Safe and Effective for Treating Dementia." 01/01/2011 - "Treatment with EGb 761(®), at a once-daily dose of 240 mg, was safe, effectively alleviated behavioral and neuropsychiatric symptoms in patients with mild to moderate dementia, and improved the wellbeing of their caregivers." 01/01/2007 - "This trial was undertaken to assess the efficacy of EGb 761 in mild to moderate dementia with neuropsychiatric features. "
2.	Alzheimer Disease (Alzheimer's Disease) 11/14/2006 - "A 5-year double-blind randomized trial of the efficacy of EGb 761 for prevention of Alzheimer disease in patients over 70 with a memory complaint." 03/27/2006 - "Research in my laboratory focuses on understanding mechanisms of action of the components of the herbal extract EGb 761 in protection against Alzheimer's disease. " 07/01/1999 - "The future of EGb 761 is undoubtedly in the promise in slowing the progression of Alzheimer's disease. " 01/15/2009 - "Several clinical trials have reported beneficial effects of the Ginkgo biloba extract EGb761 in the prevention and therapy of cognitive disorders including Alzheimer's disease (AD). " 08/01/2008 - "GuidAge study: a 5-year double blind, randomised trial of EGb 761 for the prevention of Alzheimer's disease in elderly subjects with memory complaints. "
3.	Reperfusion Injury 10/01/2014 - "The protective effects of Ginkgo biloba EGb761 extract against renal ischemia-reperfusion injury in rats." 09/01/2001 - "[Protective effects of a Ginkgo biloba extract (EGb 761) on ischemia-reperfusion injury]." 06/01/1994 - "These results indicate that EGb 761 protects against cardiac ischemia-reperfusion injury and suggest that the protective effects of EGb 761 depend on its antioxidant properties." 01/01/2002 - "The aim of this study was to determine the effect of Ginkgo Biloba (EGb 761) on reperfusion injury of the small bowel. " 06/01/1994 - "In the present study, effects of EGb 761 on cardiac ischemia-reperfusion injury were investigated from the point of view of recovery of mechanical function as well as the endogenous antioxidant status of ascorbate. "
4.	Anoxia (Hypoxia) 08/01/2011 - "This study investigates the influence of age and of acute respiratoric hypoxia on parameters of oxidative stress in different brain regions of Wistar rats and the protective effects of Ginkgo extract (EGb 761) as a radical scavenger. " 04/01/2011 - "The purpose of this study is to investigate the protective effects of Ginkgo biloba extract (EGb 761) in rat pups with hypoxia/reoxygenation (H/R)-induced bowel injury. " 01/01/2004 - "The aim of this study was to investigate the effects of in vivo and in vitro anoxia and reoxygenation on the oxidative phosphorylation of brain mitochondria and to study the protective effects of Ginkgo biloba extract (EGb 761). " 09/01/1999 - "The present study investigated the protective effects of Ginkgo biloba extract (EGb 761) on rat liver mitochondrial damage induced by in vitro anoxia/reoxygenation. " 01/01/1996 - "Myocardium-protective effects of Ginkgo biloba extract (EGb 761) in old rats against acute isobaric hypoxia. "
5.	Tinnitus 01/01/2009 - "It was shown that monotherapy with tanakan effectively improved the hearing function and had the most pronounced beneficial effect on subjective tinnitus. " 05/01/2002 - "The objective of the present study in 60 patients with chronic tinnitus aurium was to confirm the efficacy of oral treatment with 2 x 80 mg Ginkgo special extract EGb 761 per day subsequent to 10-day EGb 761 infusion treatment. " 05/01/2002 - "The efficacy of Ginkgo special extract EGb 761 in patients with tinnitus." 01/01/2014 - "Following an earlier study we here tested the potential effectiveness of prophylactic EGb 761 treatment against NIHL and tinnitus development in the Mongolian gerbil. " 01/11/2001 - "In a systematic search of the literature 19 clinical trials investigating the effects of tinnitus treatment with Ginkgo biloba special extract EGb 761 were identified and evaluated. "

Related Drugs and Biologics

1.	donepezil (Aricept)
2.	Ginkgo biloba extract 761 (Rokan)
3.	rivastigmine (Exelon)
4.	Cholinesterase Inhibitors (Anticholinesterases)
5.	Memantine (Namenda)
6.	Galantamine (Galanthamine)
7.	Tacrine (Cognex)
8.	Reactive Oxygen Species (Oxygen Radicals)
9.	Superoxide Dismutase
10.	Hydrogen Peroxide (Hydroperoxide)

Related Therapies and Procedures

1.	Oral Administration
2.	Caloric Restriction
3.	Activities of Daily Living (ADL)
4.	Rejuvenation
5.	Injections