tin etiopurpurin (SnET2)

01/01/1988 - "In 30-day tumor regrowth studies, 70% of animals treated with the metallopurpurin derivative SnET2 were free of tumors while 50% of the animals treated with the free-base purpurin ET2 were free of tumor. "
10/01/2003 - "These experiments revealed that the addition of UDCA to a PDT protocol promoted inhibition of tumor growth, a phenomenon unrelated to either altered SnET2 biodistribution or the level of vascular shutdown during irradiation. "
01/01/2003 - "This study indicates that more photon absorption is needed for tumor necrosis with AlClPc than for either SnET2 or porfimer sodium."
11/01/1990 - "Tin(IV) etiopurpurin dichloride (SnET2 x 2Cl) is a photosensitizer which has been shown to be an effective photodynamic agent for the treatment of transplantable animal tumors in vivo. "
04/01/1998 - "For clinical PDT of most adult intracranial neoplasms ALA-induced PpIX appears to be promising, and SnET2 (liposomal) has potential for selective tumor destruction with relative sparing of white matter. "

04/01/1998 - "For clinical PDT of most adult intracranial neoplasms ALA-induced PpIX appears to be promising, and SnET2 (liposomal) has potential for selective tumor destruction with relative sparing of white matter. "

12/01/1994 - "Gross and histologic examination of SnET2 photosensitized prostates treated transurethrally with 285 joules per cm. of red light (660 nm.) showed hemorrhagic necrosis as much as 1 cm. from the urethral wall. "
01/01/2003 - "This study indicates that more photon absorption is needed for tumor necrosis with AlClPc than for either SnET2 or porfimer sodium."
04/01/1998 - "The photodynamic threshold dose values for the four photosensitizers, Photofrin, 5-aminolevulinic acid (ALA)-induced Protoporphyrin IX (PpIX), Tin Ethyl Etiopurpurin (SnET2), and chloroaluminum phthalocyanine (AlClPc), were determined using measured light fluence distributions, photosensitizer concentration in tissue, and histologically-determined extent of necrosis following PDT. "

10/01/2003 - "In this study, we examined the ability of UDCA to promote tumor control by PDT in the mouse, using the radiation-induced fibrosarcoma tumor and the photosensitizing agent tin etiopurpurin (SnET2). "

02/01/1998 - "Photodynamic therapy in the management of metastatic cutaneous adenocarcinomas: case reports from phase 1/2 studies using tin ethyl etiopurpurin (SnET2)."