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interleukin 2-diphtheria toxin

chimeric product of gene fusion

Also Known As:

IL-2-diphtheria toxin

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Glycosyltransferases: 784
      - Pentosyltransferases
        ADP Ribose Transferases: 198
        Diphtheria Toxin: 708
        interleukin 2-diphtheria toxin: 1
Biological Factors: 2472
- Intercellular Signaling Peptides and Proteins: 29768
  - Cytokines: 164289
    - Interleukins: 25257
      - Interleukin-2: 17447
        interleukin 2-diphtheria toxin: 1
    - Lymphokines: 811
      - Interleukin-2: 17447
        interleukin 2-diphtheria toxin: 1
- Biological Toxins: 20
  - Bacterial Toxins: 814
    - Diphtheria Toxin: 708
      - interleukin 2-diphtheria toxin: 1
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Interleukins: 25257
        Interleukin-2: 17447
        interleukin 2-diphtheria toxin: 1
      - Lymphokines: 811
        Interleukin-2: 17447
        interleukin 2-diphtheria toxin: 1
  - Recombinant Proteins: 2754
    - Recombinant Fusion Proteins: 333
      - interleukin 2-diphtheria toxin: 1
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Interleukins: 25257
        Interleukin-2: 17447
        interleukin 2-diphtheria toxin: 1
      - Lymphokines: 811
        Interleukin-2: 17447
        interleukin 2-diphtheria toxin: 1

Experts

1.	Albu, Diana I: 1 article (01/2017)
2.	Bao, Xingfeng: 1 article (01/2017)
3.	Chen, Qian: 1 article (01/2017)
4.	Huang, Kuan-Chun: 1 article (01/2017)
5.	Ingersoll, Christy: 1 article (01/2017)
6.	Kumar, Namita: 1 article (01/2017)
7.	Kuznetsov, Galina: 1 article (01/2017)
8.	Leacu, Sarah: 1 article (01/2017)
9.	Lee, Winnie: 1 article (01/2017)
10.	Liu, Diana: 1 article (01/2017)

Related Diseases

1.

Neoplasms (Cancer)

01/01/2017 - "Furthermore, co-administration of E7046 and E7777, an IL-2-diphtheria toxin fusion protein that preferentially kills Tregs, synergistically disrupted the myeloid and Treg immunosuppressive networks, resulting in effective and durable anti-tumor immune responses in mouse tumor models. "
01/01/2017 - "EP4 Antagonism by E7046 diminishes Myeloid immunosuppression and synergizes with Treg-reducing IL-2-Diphtheria toxin fusion protein in restoring anti-tumor immunity."

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	E7046