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2- (2- hydroxy- 4- methylphenyl)aminothiazole
structure given in first source; cpd is also a free radical scavenger
Also Known As:
CBS 113A; CBS-113 A; Phenol, 5-methyl-2-(2-thiazolylamino)-, monohydrochloride
Networked:
1
relevant articles (
1
outcomes,
1
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Sulfur Compounds: 278
Thiazoles: 392
2-(2-hydroxy-4-methylphenyl)aminothiazole: 1
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Thiazoles: 392
2-(2-hydroxy-4-methylphenyl)aminothiazole: 1
Related Diseases
1.
Scleritis (Episcleritis)
01/01/1991 - "
CBS 113A was not effective against severe episcleritis.
"
01/01/1991 - "
Our results show that CBS 113A is effective in reducing the signs of conjunctival and episcleral inflammation in mild episcleritis within the first week of administration of the drug (Day 3: Total Score p = 0.0013, Conjunctival Injection p = 0.017, Episcleral Injection p = 0.0018 and Day 7: Total Score p = 0.01, Conjunctival Injection p = 0.014, Episcleral Injection p = 0.027).
"
01/01/1991 - "
A randomised double blind trial of 2-(2-Hydroxy-4-methylphenyl) Aminothiazole Hydrochloride 0.1% (CBS 113A) versus placebo was carried out in 43 eyes with episcleritis.
"
01/01/1991 - "
A randomised double blind trial comparing the treatment of episcleritis with topical 2-(2-Hydroxy-4-methylphenyl) Aminothiazole Hydrochloride 0.1% (CBS 113A) and placebo.
"
2.
Inflammation (Inflammations)
01/01/1991 - "
Our results show that CBS 113A is effective in reducing the signs of conjunctival and episcleral inflammation in mild episcleritis within the first week of administration of the drug (Day 3: Total Score p = 0.0013, Conjunctival Injection p = 0.017, Episcleral Injection p = 0.0018 and Day 7: Total Score p = 0.01, Conjunctival Injection p = 0.014, Episcleral Injection p = 0.027).
"
Related Drugs and Biologics
1.
2-aminothiazole