Haemophilus influenzae HibTITER protein

type b capsular polysaccharide of Hib-vaccine is conjugated to CRM 197

Also Known As:

HibTITER protein, Haemophilus influenzae; CRM197-Hib protein, Haemophilus influenzae; HIB capsular polysaccharide-mutant diphtheria toxin conjugate protein, Haemophilus influenzae; Haemophilus influenzae type b oligosaccharide vaccine-CRM 197 conjugate; HbOC protein, Haemophilus influenzae; Hib-Oligo-CRM197 protein, Haemophilus influenzae; Hib-titer protein, Haemophilus influenzae; PRP-CRM vaccine, Haemophilus influenzae; HibTITER

Networked: 8 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Podda, Audino: 2 articles (01/2004 - 06/2003)
2.	Viviani, Simonetta: 2 articles (01/2004 - 06/2003)
3.	Aspinall, Sanet: 1 article (01/2004)
4.	Banzhoff, Angelika: 1 article (01/2004)
5.	Bianchini, Massimo: 1 article (01/2004)
6.	Hoosen, Anwar A: 1 article (01/2004)
7.	Matjila, Maila J: 1 article (01/2004)
8.	Nacci, Pantaleo: 1 article (01/2004)
9.	Palweni, Chapman W: 1 article (01/2004)
10.	Phohu, Thabo C: 1 article (01/2004)

Related Diseases

1.	Diphtheria 05/01/1997 - "Immunogenicity of Haemophilus influenzae b conjugate vaccine (HibTITER) and safety of HibTITER and a combination vaccine of diphtheria, tetanus, pertussis and HibTITER in infants two months of age: a preliminary report." 09/01/1998 - "A study was undertaken to evaluate the safety and immunogenicity of a combination vaccine (TETRAMUNE) of conjugate Haemophilus influenzae type b (Hib) vaccine (HibTITER) and DTP (Diphtheria, Tetanus and Pertussis) vaccine. " 09/01/1998 - "Immunogenicity and safety of Haemophilus influenzae type b conjugate vaccine (HibTITER) and a combination vaccine of diphtheria, tetanus, pertussis and HibTITER (TETRAMUNE) in two-month-old infants." 01/01/2001 - "ACEL-Immune contains diphtheria and tetanus toxoids with acellular pertussis vaccine adsorbed, and HibTITER contains the Haemophilus influenzae B conjugate vaccine (diphtheria CRM197 protein conjugate) [239655]. " 05/01/1999 - "The immunogenic responses and local reactions to four Haemophilus influenzae type b (Hib) conjugate vaccines licensed for primary immunisation (Hiberix, ActHib, Pedvax, HibTITER) when administered concomitantly but in the opposite thigh with a candidate diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliovirus vaccine were studied in 549 healthy infants at 3, 4.5 and 6 months of age. "
2.	Tetanus 05/01/1997 - "A study was undertaken to evaluate the safety and immunongenicity of a conjugate Haemophilus influenzae type b (Hib) vaccine (HibTITER) when administered concurrently with DTP (diphteria, tetanus and pertussis) vaccine in separate syringes. " 05/01/1997 - "Immunogenicity of Haemophilus influenzae b conjugate vaccine (HibTITER) and safety of HibTITER and a combination vaccine of diphtheria, tetanus, pertussis and HibTITER in infants two months of age: a preliminary report." 09/01/1998 - "A study was undertaken to evaluate the safety and immunogenicity of a combination vaccine (TETRAMUNE) of conjugate Haemophilus influenzae type b (Hib) vaccine (HibTITER) and DTP (Diphtheria, Tetanus and Pertussis) vaccine. " 09/01/1998 - "Immunogenicity and safety of Haemophilus influenzae type b conjugate vaccine (HibTITER) and a combination vaccine of diphtheria, tetanus, pertussis and HibTITER (TETRAMUNE) in two-month-old infants." 01/01/2001 - "ACEL-Immune contains diphtheria and tetanus toxoids with acellular pertussis vaccine adsorbed, and HibTITER contains the Haemophilus influenzae B conjugate vaccine (diphtheria CRM197 protein conjugate) [239655]. "
3.	Whooping Cough (Pertussis) 01/01/2004 - "In total, 331 babies were immunised with either Vaxem Hib (N = 167) or HibTITER (N = 164) vaccine at 6, 10 and 14 weeks of age, in parallel with oral polio, diphtheriatetanus-pertussis and hepatitis B vaccines. " 05/01/1997 - "Immunogenicity of Haemophilus influenzae b conjugate vaccine (HibTITER) and safety of HibTITER and a combination vaccine of diphtheria, tetanus, pertussis and HibTITER in infants two months of age: a preliminary report." 09/01/1998 - "Immunogenicity and safety of Haemophilus influenzae type b conjugate vaccine (HibTITER) and a combination vaccine of diphtheria, tetanus, pertussis and HibTITER (TETRAMUNE) in two-month-old infants." 05/01/1999 - "The immunogenic responses and local reactions to four Haemophilus influenzae type b (Hib) conjugate vaccines licensed for primary immunisation (Hiberix, ActHib, Pedvax, HibTITER) when administered concomitantly but in the opposite thigh with a candidate diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliovirus vaccine were studied in 549 healthy infants at 3, 4.5 and 6 months of age. " 09/01/1999 - "The objectives of this study were (1) to determine the safety and immunogenicity of heptavalent pneumococcal CRM197 conjugate (PNCRM7) vaccine in infants and (2) to determine the effect of concurrent hepatitis B immunization during the primary series and the effect of concurrent diphtheria and tetanus toxoid and acellular pertussis [DTaP (ACEL-IMUNE)] and conjugate CRM197 Haemophilus influenzae type b [HbOC (HibTITER) immunization at time of the booster dose on the safety and immunogenicity of PNCRM7and these other concurrently administered vaccines. "
4.	Hepatitis B 09/15/2001 - "To those aged 2 and 6 months (group 1: 108 children) it was administered the association DTPw + Hepatitis B + Hib (Tritanrix-HB + Hiberix) with a volume of injection of 0,5 ml, and to those aged 4 months (group 2: 120 children) the association DTPw + Hib (Anatoxal Diteper + Hibtiter) with a volume of 1 ml. The injection was applied in the thigh and paracetamol was indicated in the following 24 hours. " 05/01/1999 - "The immunogenic responses and local reactions to four Haemophilus influenzae type b (Hib) conjugate vaccines licensed for primary immunisation (Hiberix, ActHib, Pedvax, HibTITER) when administered concomitantly but in the opposite thigh with a candidate diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliovirus vaccine were studied in 549 healthy infants at 3, 4.5 and 6 months of age. " 09/01/1999 - "The objectives of this study were (1) to determine the safety and immunogenicity of heptavalent pneumococcal CRM197 conjugate (PNCRM7) vaccine in infants and (2) to determine the effect of concurrent hepatitis B immunization during the primary series and the effect of concurrent diphtheria and tetanus toxoid and acellular pertussis [DTaP (ACEL-IMUNE)] and conjugate CRM197 Haemophilus influenzae type b [HbOC (HibTITER) immunization at time of the booster dose on the safety and immunogenicity of PNCRM7and these other concurrently administered vaccines. "
5.	Poliomyelitis (Polio) 01/01/2004 - "In total, 331 babies were immunised with either Vaxem Hib (N = 167) or HibTITER (N = 164) vaccine at 6, 10 and 14 weeks of age, in parallel with oral polio, diphtheriatetanus-pertussis and hepatitis B vaccines. "

Related Drugs and Biologics

1.	Vaccines
2.	Pertussis Vaccine
3.	CRM197 (non-toxic variant of diphtheria toxin)
4.	Diphtheria-Tetanus-acellular Pertussis Vaccines (Tripedia)
5.	Tetanus Toxoid (Vaccine, Tetanus)
6.	Heptavalent Pneumococcal Conjugate Vaccine (Prevnar)
7.	diphtheria-tetanus-pertussis-haemophilus b conjugate vaccine (TriHIBit)
8.	Conjugate Vaccines
9.	Hiberix
10.	Hepatitis B Vaccines (Hepatitis B Vaccine)