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phosphatidylinositol-3-phosphatase

Also Known As:

INTP 3-phosphatase; inositol polyphosphate 3-phosphatase; phosphatidylinositol 3-phosphatase

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Esterases: 1574
      - Phosphoric Monoester Hydrolases: 7477
        phosphatidylinositol-3-phosphatase: 3

Experts

1.	Haucke, Volker: 1 article (01/2016)
2.	Ketel, Katharina: 1 article (01/2016)
3.	Krauss, Michael: 1 article (01/2016)
4.	Laporte, Jocelyn: 1 article (01/2016)
5.	Müller, Rainer: 1 article (01/2016)
6.	Nicot, Anne-Sophie: 1 article (01/2016)
7.	Puchkov, Dmytro: 1 article (01/2016)
8.	Schultz, Carsten: 1 article (01/2016)
9.	Subramanian, Devaraj: 1 article (01/2016)
10.	Wieffer, Marnix: 1 article (01/2016)

Related Diseases

1.	Congenital Structural Myopathies (Centronuclear Myopathy) 01/21/2016 - "Here we report that surface delivery of endosomal cargo requires hydrolysis of PI(3)P by the phosphatidylinositol 3-phosphatase MTM1, an enzyme whose loss of function leads to X-linked centronuclear myopathy (also called myotubular myopathy) in humans. "
2.	Neoplasms (Cancer) 02/15/2000 - "The tumor suppressor PTEN regulates T cell survival and antigen receptor signaling by acting as a phosphatidylinositol 3-phosphatase."
3.	Ascites 06/01/2014 - "Here we demonstrate that mTOR activity in Ehrlich Lettré ascites (ELA) cells is transiently increased within minutes following osmotic cell swelling and that inhibition of phosphatidylinositol-3-phosphatase (PTEN) counteracts the upstream phosphatidylinositol kinase and potentiates mTOR activity. "

Related Drugs and Biologics

1.	Antigen Receptors (Antigen Receptor)
2.	Phosphotransferases (Kinase)
3.	Phosphatidylinositols (Phosphatidylinositol)
4.	Enzymes