combretastatin A-2

isolated from Combretum caffrum; RN from first source; structure given in first source

Also Known As:

3,4-(methylenedioxy)-5-methoxy-3'-hydroxy-4'-methoxystilbene

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 03/27/2009 - "Compared to combretastatin A-2 (1), stilstatin 1 (2) has an additional vicinal hydroxy group on the B ring, the presence of which was detrimental to the cancer cell line potency; in vivo, however, compound 2 would be predicted to have greater anticancer activity resulting from the o-quinone mechanism of action analogous to that of combretastatin A-1 (4). "