HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

RG 6866

structure given in first source

Also Known As:

N-methyl-4-benzyloxyphenylacetohydroxamic acid; REV 6866; REV-6866; RG-6866

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133

Related Diseases

1.

Anaphylaxis (Anaphylactic Shock)

11/01/1989 - "In the pulmonary anaphylaxis model, significant (p less than 0.05) inhibition of the mortality was observed within 30 min and maintained through four hours after treatment with RG 6866 (50 mg/kg i.g.). "
11/01/1989 - "In actively sensitized guinea pigs pretreated with indomethacin, propranolol and pyrilamine, RG 6866 inhibited antigen-induced systemic anaphylaxis and LTD4-dependent bronchoconstriction in a dose-dependent manner following oral administration. "
01/01/1989 - "In an attempt to study this problem, two 5-lipoxygenase inhibitors, the novel compound RG 6866, N-methyl-4-benzyloxyphenyl acetohydroxamic acid, and AA 861 have been examined in Langendorff-perfused guinea pig hearts undergoing cardiac anaphylaxis and compared to indomethacin and LY 171883, a cyclooxygenase inhibitor and a leukotriene antagonist, respectively. "

Related Drugs and Biologics

1.	Indomethacin (Indometacin)
2.	Leukotriene Antagonists (Leukotriene Receptor Antagonists)
3.	Cyclooxygenase Inhibitors
4.	Lipoxygenase Inhibitors
5.	LY 171883
6.	2,3,5- trimethyl- 6- (12- hydroxy- 5,10- dodecadiynyl)- 1,4- benzoquinone
7.	acetohydroxamic acid (Lithostat)
8.	Pyrilamine (Mepyramine)
9.	Propranolol (Inderal)
10.	Antigens

Related Therapies and Procedures

1.	Aftercare (After-Treatment)
2.	Oral Administration