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7- bis(beta- chloroethyl)aminomethyl- 6,14- endoethenotetrahydrooripavine

structure given in first source; RN refers to (5alpha,7alpha)-isomer; RN for compound without isomeric designation not avail 11/89; opioid agonist

Also Known As:

alpha-CAM

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Birukova, Anna: 1 article (07/2003)
2.	Borbiev, Talaibek: 1 article (07/2003)
3.	Crow, Michael T: 1 article (07/2003)
4.	Garcia, Joe G N: 1 article (07/2003)
5.	Liu, Feng: 1 article (07/2003)
6.	Verin, Alexander D: 1 article (07/2003)
7.	Deguchi, S: 1 article (07/2001)
8.	Mima, K: 1 article (07/2001)
9.	Yamauchi, T: 1 article (07/2001)

Related Diseases

1.	Memory Disorders (Memory Loss) 09/01/1996 - "Since previous studies have shown alpha-CaM kinase to be involved in memory, its association with PHF may have important implications in understanding memory loss in AD. "
2.	Neuroblastoma 07/13/2001 - "Functional analysis of alpha CaM kinase II promoter deletion mutants fused to a reporter gene in neuroblastoma, including N18TG2, NG108-15, and CAD cells revealed strong transcriptional activity localized 100-145 bp, and a potent silencer 199-275 bp upstream of the transcription start site. "
3.	Infections 07/01/2003 - "Similar to thrombin, infection with a constitutively active adenoviral alpha-CaM kinase II construct induced significant ERK activation, indicating that CaM kinase II activation lies upstream of ERK. "

Related Drugs and Biologics

1.	Phosphotransferases (Kinase)
2.	Calcium-Calmodulin-Dependent Protein Kinase Type 2
3.	Thrombin