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4- methoxy- 8- (ribofuranosylamino)pyrimido(5,4- d)pyrimidine

structure given in first source

Also Known As:

MRPP

Networked: 8 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidine Nucleosides: 50
      - 4-methoxy-8-(ribofuranosylamino)pyrimido(5,4-d)pyrimidine: 8
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Pyrimidine Nucleosides: 50
    - 4-methoxy-8-(ribofuranosylamino)pyrimido(5,4-d)pyrimidine: 8

Experts

1.	Jenkins, Carly: 2 articles (01/2021 - 01/2019)
2.	Whitman, Mark: 2 articles (01/2021 - 01/2019)
3.	Adams, Lewis: 1 article (01/2019)
4.	Sabapathy, Surendran: 1 article (01/2019)
5.	Bessa, L G P: 1 article (11/2012)
6.	Bittencourt, L K: 1 article (11/2012)
7.	Coutinho, A C: 1 article (11/2012)
8.	Domingues, R C: 1 article (11/2012)
9.	Junqueira, F P: 1 article (11/2012)
10.	Lima, C M A O: 1 article (11/2012)

Related Diseases

1.	Pulmonary Embolism 11/01/2012 - "Pulmonary multidetector CT angiography (MDCTA), pulmonary MR angiography (MRA) and MR-derived pulmonary perfusion (MRPP) imaging are non-invasive imaging techniques for the differential diagnosis of PH. MDCTA is considered the gold standard for the diagnosis of pulmonary embolism, one of the most common causes of PH. MRA and MRPP are promising techniques that do not require the use of ionising radiation or iodinated contrast material, and can be useful for patients for whom such material cannot be used. "
2.	Myocardial Ischemia (Ischemic Heart Diseases) 01/01/2021 - "The current study demonstrates the substantial prognostic power of MRPP over both APMHR and HRR% to predict CV events following an otherwise negative ESE for myocardial ischemia." 01/01/2019 - "The results suggest that regardless of functional capacity, individuals whose EST is terminated at maximal fatigue, with no electrocardiogram evidence or symptoms of myocardial ischemia and yields an MRPP > 25000, do not require further downstream testing. "
3.	Cognitive Dysfunction 12/01/2003 - "To characterize the responsiveness of the Montréal Rehabilitation Performance Profile (MRPP); to measure the differential effectiveness of a task-specific (TS) and a task-nonspecific (TNS) motor learning format to promote alternating stair descent in children with cognitive impairments; and to evaluate the relevance of the MRPP to evidence-based practice. "
4.	Colorectal Neoplasms (Colorectal Cancer) 11/29/1994 - "We examined the cytotoxicity, biochemical effects and metabolism of 4-methoxy-8-(beta-D-ribofuranosylamino)pyrimido[5,4-d]pyrimidine (MRPP), a synthetic nucleoside inhibitor of phosphoribosylpyrophosphate synthetase, in HCT 116 human colorectal cancer cells. "
5.	Lung Neoplasms (Lung Cancer) 01/01/2023 - "According to the ANOSIM and MRPP analysis, there was a difference between the NLRP3-/- lung cancer group and the NLRP3-/- control group (P < 0.05). "

Related Drugs and Biologics

1.	Contrast Media
2.	Nucleosides
3.	Ligases (Synthetase)
4.	Captopril (Capoten)
5.	pyrimidine
6.	2-(4-toluidino)-6-naphthalenesulfonic acid (TNS)