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ovothiol A (U23)

structure given in first source

Also Known As:

U23; 1-N-methyl-4-mercaptohistidine; L-Histidine, 5-mercapto-3-methyl-

Networked: 13 relevant articles (0 outcomes, 5 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Cyclic Amino Acids: 3
    - Histidine: 2980
      - Methylhistidines: 50
        ovothiol A: 13

Experts

1.	Castellano, Immacolata: 3 articles (01/2018 - 07/2014)
2.	Palumbo, Anna: 3 articles (01/2018 - 07/2014)
3.	Leo, Peter: 2 articles (07/2022 - 12/2021)
4.	Mujika, Iñigo: 2 articles (07/2022 - 12/2021)
5.	Napolitano, Alessandra: 2 articles (01/2018 - 07/2014)
6.	Campos-Donaire, Antonio: 1 article (07/2022)
7.	Codella, Roberto: 1 article (07/2022)
8.	Faelli, Emanuela: 1 article (07/2022)
9.	Filipas, Luca: 1 article (07/2022)
10.	Gallo, Gabriele: 1 article (07/2022)

Related Diseases

1.	Myocardial Infarction 01/01/2022 - "The current study reveals the ability to use Ovothiol-A in the treatment of myocardial infarction." 01/01/2022 - "Modulatory effect of Ovothiol-A on myocardial infarction induced by epinephrine in rats." 01/01/2022 - "Ovothiol-A possessed a therapeutic effect against epinephrine-induced myocardial infarction. "
2.	Liver Cirrhosis (Hepatic Cirrhosis) 01/01/2018 - "In this study, we have investigated for the first time the effect of ovothiol A, π-methyl-5-thiohistidine, isolated from sea urchin eggs on an in vivo murine model of liver fibrosis. " 01/01/2018 - "Overall, these findings indicate that ovothiol A has significant antifibrotic properties and can be considered as a new marine drug or dietary supplement in potential therapeutic strategies for the treatment of liver fibrosis." 01/01/2018 - "Finally, we provided evidence that the attenuation of liver fibrosis by ovothiol A treatment can be regulated by the expression and activity of the membrane-bound γ-glutamyl-transpeptidase (GGT), which is a key player in maintaining intracellular redox homoeostasis. " 01/01/2018 - "Mice were intraperitoneally injected with carbon tetrachloride (CCl4) to induce liver fibrosis and treated with ovothiol A at the dose of 50 mg/kg 3 times a week for 2 months. "
3.	Mental Fatigue 07/01/2020 - "The current study collected survey data from English academy soccer players (n = 256; age groups - U14 - U23), with questions comprising of five themes (descriptors of physical and mental fatigue, travel, education, match-play and fixture congestion). "
4.	Carcinoma (Carcinomatosis) 07/07/2014 - "In this study, we show that treatment of a human liver carcinoma cell line, Hep-G2, with ovothiol A, isolated from Paracentrotus lividus oocytes, results in a decrease of cell proliferation in a dose-dependent manner. "
5.	COVID-19 12/21/2021 - "The aim of this study was to investigate how the COVID-19 restrictions affected training and performance physiology measures in U23 elite cyclists. " 12/21/2021 - "These results indicate that COVID-19 restrictions did not negatively affect training characteristics and physiological performance measures in U23 elite cyclists for a period of <30 days. " 12/21/2021 - "Influence of COVID-19 Restrictions on Training and Physiological Characteristics in U23 Elite Cyclists."

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4.	Interleukin-6 (Interleukin 6)
5.	Estrogen Receptors
6.	Proteins (Proteins, Gene)
7.	Glycoproteins (Glycoprotein)
8.	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)
9.	Free Radicals
10.	Fibroblast Growth Factors (Fibroblast Growth Factor)