HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

Ro 23-6457

Also Known As:

3,7-dimethyl-9-(2-trifluoromethyl-6-(nonyloxyl)phenyl)-2,4,6,8-NTA; Ro-23-6457; all-E-3,7-dimethyl-9-(2-trifluoromethyl-6-(nonyloxyl)phenyl)-2,4,6,8-nonatetratetraenoic acid

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Experimental Arthritis 06/01/1989 - "Ro 23-6457, (all-E)-3,7-dimethyl-9-[2-(trifluoromethyl)-6-(nonyloxy)phenyl]-2, 4,6,8- nonatetraenoic acid, and Ro 23-2895, (all-E)-9-[2-(nonyloxy)phenyl]-3,7-dimethyl-2,4,6,8-nonatetraen oic acid, are two novel retinoid analogs which exhibit antiinflammatory activity in both the developing and the established rat adjuvant arthritis models [8]. "
2.	Arthritis (Polyarthritis) 06/01/1989 - "Prophylactic treatment (p.o.) of rats with adjuvant-induced arthritis (AA) with two retinoid-like 2,4,6,8-nonatetraenoic acids (NTA), Ro 23-6457 and Ro 23-2895, significantly reduced hind paw swelling between days 10-23 and the level of plasma fibrinogen (MED approximately 25 mumoles/kg). "

Related Drugs and Biologics

1.	Retinoids
2.	Acids
3.	Ro 23-2895
4.	Fibrinogen (Factor I)