phospholine

from Streptomyces hygroscopicus; structure given in J Antibiot (Tokyo) 1989;42(9):1339; do not confuse with phospholine iodide which is a print entry term to ECHOTHIOPHATE IODIDE

Networked: 14 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Honkanen, Richard E: 1 article (01/2007)
2.	Ni, Li: 1 article (01/2007)
3.	Swingle, Mark: 1 article (01/2007)

Related Diseases

1.	Esotropia (Esophoria) 04/01/1987 - "[Value of postoperative phospholine in esotropias]." 08/01/1984 - "[Role of phospholine in the postoperative treatment of esotropia]." 04/01/1968 - "[First results of the use of iodine phospholine in the management of esotropias]." 02/01/1964 - "PRELIMINARY REPORT ON 0.06-PERCENT PHOSPHOLINE (ECHOTHIOPHATE) IODIDE IN THE MANAGEMENT OF ESOTROPIA."
2.	Poisoning 05/01/1980 - "A high degree of AChE inhibition was observed in the brain after chlorphenvinphos poisoning (activity fall to 15--30%) and a slight decrease of AChE activity after administration of phospholine independently of the route. " 09/01/1975 - "Acetylcholinesterase activity in the rat tissues during chronic phospholine poisoning." 01/01/1981 - "The observations prove that the efficiency of the basic therapeutic mixture during 24 hrs of observation of mice poisonings with AO 217 and DFP was respectively: 2.31 x and 2.64 x. In phospholine poisonings no increase in therapeutic effects were found." 01/01/1981 - "This paper was aimed at the observation of trimethadione therapeutic effects while this preparation was used as an agent supplementing the standard therapeutic mixture (cholinolytic and reactivator) for mice poisoning with phospholine--a compound of AO 217 and DEP. "
3.	Glaucoma 06/01/1976 - "In an initial clinical trial, one member of the new series (alkyl = C2H5) caused a significant decrease of intraocular pressure in aphakic glaucoma, while phospholine proved to be ineffective." 08/01/1960 - "Phospholine iodine (217MI) and demecarium bromide (BC48) in the management of glaucoma."
4.	Angle-Closure Glaucoma (Glaucoma, Angle Closure) 02/01/1965 - "PHOSPHOLINE (ECHOTHIOPHATE) IODIDE IN CHRONIC NARROW-ANGLE GLAUCOMA."
5.	Strabismus (Squint) 01/01/1971 - "[Phospholine in the treatment of squint]."

Related Drugs and Biologics

1.	Iodine
2.	Echothiophate Iodide (Phospholine Iodide)
3.	Microcystins
4.	Therapeutic Uses
5.	Okadaic Acid
6.	Cholinergic Antagonists (Anticholinergics)
7.	Cholinergic Agents (Cholinergics)
8.	Tubocurarine (Tubocurarine Chloride)
9.	Trimethadione (Tridione)
10.	Soman