A18Famide

an endogenous mammalian FMRFamide (Phe-Met-Arg-Phe-NH2)-related octadecapeptide; an orphan G-protein coupled receptor peptide; a morphine-modulating neuropeptide

Also Known As:

A-18-F-amide; A-18-Famide; A18Fa; Ala-Gly-Glu-Gly-Leu-Ser-Ser-Pro-Phe-Trp-Ser-Leu-Ala-Ala-Pro-Gln-Arg-Phe-NH2; NPAF peptide; neuropeptide AF

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - A18Famide: 5

Experts

1.	Cline, M A: 2 articles (06/2010 - 07/2009)
2.	Newmyer, B A: 2 articles (06/2010 - 07/2009)
3.	Osugi, T: 1 article (06/2015)
4.	Tsutsui, K: 1 article (06/2015)
5.	Ubuka, T: 1 article (06/2015)
6.	Siegel, P B: 1 article (06/2010)
7.	Smith, M L: 1 article (07/2009)
8.	Kotovych, George: 1 article (06/2003)
9.	Miskolzie, Mark: 1 article (06/2003)

Related Diseases

1.	Pain (Aches) 06/01/2015 - "From a structural point of view, pain modulatory neuropeptides, such as neuropeptide FF (NPFF) and neuropeptide AF, share a C-terminal PQRFamide motif. " 06/01/2003 - "The tertiary structure of the pain modulating and anti-opiate neuropeptide, human neuropeptide AF (NPAF) (the sequence is AGEGLNSQFWSLAAPQRF-NH(2)), was determined by (1)H-NMR. "
2.	Anorexia 06/01/2010 - "Neuropeptide AF differentially affects anorexia in lines of chickens selected for high or low body weight." 07/01/2009 - "Neuropeptide AF (NPAF), a member of the RFamide family, is encoded by the same gene as neuropeptide FF (NPFF), which causes short-term anorexia. "
3.	Hyperphagia (Overeating) 06/01/2010 - "The recently discovered anorectic effect of neuropeptide AF (NPAF) has not been studied in hypo-and hyperphagia animal models. "
4.	Body Weight (Weight, Body) 06/01/2010 - "Neuropeptide AF differentially affects anorexia in lines of chickens selected for high or low body weight."
5.	Bites and Stings (Sting) 03/01/1991 - "Intracerebroventricular (ICV) administrations of F8Fa and A18Fa (0.10-10 micrograms) reduced, in a dose-dependent manner, the number of bites to obtain defeat in the subordinate mice during the agonistic encounters, as well as attenuating defeat-induced analgesia, with F8Fa having a greater inhibitory effect than A18Fa. "

Related Drugs and Biologics

1.	Neuropeptides
2.	phenylalanyl- leucyl- phenylalanyl- glutaminyl- prolyl- glutaminyl- arginyl- phenylalaninamide
3.	Opiate Alkaloids
4.	Appetite Depressants (Anorectics)
5.	arginylphenylalaninamide

Related Therapies and Procedures

1.	Analgesia