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ptilocaulin

structure given in first source; RN given refers to (3aS-(3aalpha,5aalpha,7alpha,8balpha))-isomer

Also Known As:

isoptilocauline; ptilocaulin, (3aS-(3aalpha,5aalpha,8aalpha,8balpha))-isomer

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinazolines: 402
      - ptilocaulin: 1

Related Diseases

1.	Neoplasms (Cancer) 07/01/1989 - "Ptilocaulin was toxic at 50 and 25 mg/kg in an in vivo L1210 tumor model and was ineffective at lower concentrations (T/Cs 100-112%). "
2.	Melanoma (Melanoma, Malignant) 07/01/1989 - "Ptilocaulin showed a fairly broad spectrum of in vitro activity against colon and mammary adenocarcinomas, melanomas, leukemias, transformed fibroblasts and normal lymphoid cells (IC50s 0.05- greater than 10 micrograms/ml). "
3.	Leukemia 07/01/1989 - "Ptilocaulin showed a fairly broad spectrum of in vitro activity against colon and mammary adenocarcinomas, melanomas, leukemias, transformed fibroblasts and normal lymphoid cells (IC50s 0.05- greater than 10 micrograms/ml). "
4.	Adenocarcinoma 07/01/1989 - "Ptilocaulin showed a fairly broad spectrum of in vitro activity against colon and mammary adenocarcinomas, melanomas, leukemias, transformed fibroblasts and normal lymphoid cells (IC50s 0.05- greater than 10 micrograms/ml). "