RS 20

16 amino acid residues given in first source; derived from the calmodulin-binding domain of MLCK binds calmodulin with high affinity; potent inhibitor of MLCK activity; inhibits contraction of skinned smooth muscle as well as phosphorylation of myosin light chains

Also Known As:

RS-20

Networked: 8 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Carrier Proteins: 12999
    - Calmodulin-Binding Proteins: 398
      - RS 20: 8

Experts

1.	Badve, Sunil: 1 article (04/2022)
2.	Kalinsky, Kevin: 1 article (04/2022)
3.	Li, Xiaoxian: 1 article (04/2022)
4.	Meisel, Jane L: 1 article (04/2022)
5.	Nguyen, Thi Truc Anh: 1 article (04/2022)
6.	O'Regan, Ruth: 1 article (04/2022)
7.	Postlewait, Lauren M: 1 article (04/2022)
8.	Zhang, Chao: 1 article (04/2022)
9.	Araya, Erika Ivanna: 1 article (11/2020)
10.	Barroso, Amanda Ribeiro: 1 article (11/2020)

Related Diseases

1.	ST Elevation Myocardial Infarction 02/01/2005 - "Data were drawn from 748 patients with open epicardial arteries and with optimal luminal results (RS <20%) following rescue/adjunctive PCI after fibrinolytic administration in six STEMI trials. "
2.	Anhedonia 09/01/2009 - "Smokers with higher levels of anhedonia reported a greater number of past failed quit attempts and a higher proportion of quit attempts that ended in rapid relapse within 24 hr, rs > .20, ps < .05. "
3.	Hypophosphatemia 01/01/2019 - "Low risk patients developed mild hypophosphatemia at a much lower percentage than high-risk RS (20% vs 33.3%, respectively). "
4.	Reye Syndrome (Reye's Syndrome) 09/01/1990 - "To produce an animal model of Reye's syndrome (RS), 20 adult male Wistar rats were given 10 repeated i.p. "
5.	Postoperative Pain 11/01/2020 - "In the postoperative pain model, rats were treated with LPS-RS (20 µg/10 µL) into the TG for three consecutive days after the incision. "

Related Drugs and Biologics

1.	Phenobarbital (Luminal)
2.	Nifedipine (Adalat)