breviscapine

10/08/2008 - "To assess whether dengzhanhua preparations are effective and safe at improving outcomes in patients with acute cerebral infarction. "
06/28/2002 - "Dengzhanhua injection in the treatment of acute cerebral infarction is safe and effective."
10/08/2008 - "Many controlled trials have been undertaken to investigate the efficacy of dengzhanhua preparations in the treatment of acute cerebral infarction. "
10/08/2008 - "Randomised and quasi-randomised controlled clinical trials of dengzhanhua preparations regardless of duration, dosage and route of administration in patients with confirmed acute cerebral infarction. "
11/15/2020 - "Clinical evidence and GRADE assessment for breviscapine injection (DengZhanHuaSu) in patients with acute cerebral infarction."

04/01/2018 - "The purpose of the present study was to investigate the effect of breviscapine injection on hepatic ischemia/reperfusion (I/R) injury in rats. "
04/01/2009 - "In the place navigation test, the mean value of escape latency in breviscapine group was significantly shorter than that in ischemia control group (P < 0.01 for lower-dose and P < 0.05 for higher-dose breviscapine group, respectively). "
11/01/2006 - "We sought to evaluate the effects of breviscapine to ameliorate graft ischemia-reperfusion (I/R) injury in a rat small bowel transplantation model. "
01/01/2016 - "The purpose of this study was to investigate the effect of breviscapine injection on hepatic ischemia and/or reperfusion injury. "
09/01/2007 - "The results demonstrate that the protective effects of scutellarin on cardiovascular and cerebrovascular ischemia were better than its mixture, breviscapine, in rats."

04/01/2009 - "These results indicate that breviscapine can improve the functions of spatial learning and memory of focal cerebral ischemia rats and the protection against the loss of ChAT immunopositive neuron in new cortex may be involved in its mechanisms."
06/01/2017 - "Breviscapine confers a neuroprotective efficacy against transient focal cerebral ischemia by attenuating neuronal and astrocytic autophagy in the penumbra."
06/01/2017 - "Our study suggests that breviscapine can provide a neuroprotection against transient focal cerebral ischemia, and this biological function is associated with attenuating autophagy in both neurons and astrocytes."
06/01/2017 - "In present study, we investigated whether breviscapine could confer a neuroprotection against cerebral ischemia injury by targeting autophagy mechanisms. "
04/01/2009 - "To investigate the effects of breviscapine on the functions of spatial learning and memory of focal cerebral ischemia rats. "

01/01/2021 - "Therefore, the present study aimed to ascertain whether pretreatment with breviscapine could improve CME-induced myocardial injury by alleviating myocardial inflammation and apoptosis. "
08/01/2018 - "The present study highlighted that breviscapine exhibited liver‑protective effects against acute hepatic injury induced by CCl4 via suppressing inflammation and apoptosis."
01/01/2021 - "Breviscapine Pretreatment Inhibits Myocardial Inflammation and Apoptosis in Rats After Coronary Microembolization by Activating the PI3K/Akt/GSK-3β Signaling Pathway."
02/15/2023 - "To study the protective effect of breviscapine against brain injury induced by intrauterine inflammation in preterm rats and its mechanism. "
02/15/2023 - "Breviscapine can inhibit inflammatory response in brain tissue of preterm rats caused by intrauterine inflammation by activating the Nrf2 pathway, and it can also inhibit microglial pyroptosis and alleviate brain injury. "

01/01/2014 - "The present study was designed to investigate the therapeutic time window and underlying therapeutic mechanism of breviscapine injection against cerebral ischemic/reperfusion injury. "
04/01/2018 - "Role of mitofusin 2 in the protective effect of breviscapine against hepatic ischemia/reperfusion injury in rats."
01/01/2016 - "Breviscapine preconditioning attenuates liver ischemia reperfusion injury via inhibiting liver oxidative stress reaction. "
01/01/2016 - "Effect of breviscapine against hepatic ischemia reperfusion injury."
09/01/2015 - "Cardioprotective effect of breviscapine: inhibition of apoptosis in H9c2 cardiomyocytes via the PI3K/Akt/eNOS pathway following simulated ischemia/reperfusion injury."