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1,3-diethyl-1-nitrosourea
structure given in first source
Also Known As:
N,N'-diethyl-N-nitrosourea; N-nitroso-N,N'-diethylurea; nitrosodiethylurea
Networked:
3
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amides: 2428
Urea: 15015
Nitrosourea Compounds: 21
Ethylnitrosourea: 850
1,3-diethyl-1-nitrosourea: 3
Nitroso Compounds: 446
Nitrosourea Compounds: 21
Ethylnitrosourea: 850
1,3-diethyl-1-nitrosourea: 3
Related Diseases
1.
Neoplasms (Cancer)
01/01/1988 - "
Although nitrosomethylurea did not induce colon tumors under these conditions, nitrosoethylurea did, together with nitrosodiethylurea and other nitrosoethylalkylureas.
"
01/01/1989 - "
Nitrosodimethylurea and nitroso-1-methyl-3-ethylurea gave rise primarily to tumors of the nervous system, whereas nitrosodiethylurea and nitroso-1-ethyl-3-methylurea gave rise to tumors of the mammary gland, lung, intestinal tract, nervous system, and testicular mesotheliomas.
"
01/30/1998 - "
To investigate the two activities, brief treatments of male F344 rats with each of three mutagens, nitrosodimethylurea, nitrosodiethylurea and nitrosobis-(2-oxopropyl)-amine, were followed by chronic treatment (40 weeks) with one of four non-mutagens, nitrosomethyl-3-carboxypropylamine, nitrosodiethanolamine, nitrosomethyl-2-hydroxypropylamine or phenobarbital, the last being a well-known promotor of liver tumors in rats.
"
2.
Nervous System Neoplasms (Neoplasms, Nervous System)
01/01/1989 - "
Nitrosodimethylurea and nitroso-1-methyl-3-ethylurea gave rise primarily to tumors of the nervous system, whereas nitrosodiethylurea and nitroso-1-ethyl-3-methylurea gave rise to tumors of the mammary gland, lung, intestinal tract, nervous system, and testicular mesotheliomas.
"
3.
Mesothelioma
01/01/1989 - "
Nitrosodimethylurea and nitroso-1-methyl-3-ethylurea gave rise primarily to tumors of the nervous system, whereas nitrosodiethylurea and nitroso-1-ethyl-3-methylurea gave rise to tumors of the mammary gland, lung, intestinal tract, nervous system, and testicular mesotheliomas.
"
Related Drugs and Biologics
1.
N,N'-dimethylnitrosourea
2.
Phenobarbital (Luminal)
3.
Mutagens
4.
Methylnitrosourea (N-Methyl-N-nitrosourea)
5.
Ethylnitrosourea (N-Ethyl-N-nitrosourea)
6.
4-(N-nitroso-N-methylamino)butyric acid