benidipine

07/01/2005 - "Overall, these results demonstrated that benidipine improved endothelial dysfunction in patients with hypertension. "
01/01/2001 - "In Study 1, ambulatory BP and physical activity were measured simultaneously in 27 patients with hypertension before and after 6 months with benidipine. "
05/15/2021 - "Benidipine (BD), which is widely used to treat hypertension, has been proved to have a beneficial effect on bone metabolism. "
01/01/2011 - "However, the long-term efficacy and safety of benidipine remain unknown in elderly Chinese patient with hypertension. "
03/08/2002 - "Benidipine may also ameliorate the morphological changes of the basilar artery in hypertension."

12/01/2013 - "The results suggested that benidipine combined with a BB appeared to be less beneficial in reducing the risk of stroke compared with the benidipine-TD combination (hazard ratio (HR): 2.31, P=0.0109). "
04/01/2012 - "Further studies will be necessary to evaluate the usefulness of benidipine combined with a β-blocker in terms of the incidence of stroke and new-onset diabetes in older patients."
01/01/2001 - "Recent trials in Japan have shown that benidipine may be more efficient than the former drug in preventing strokes in the elderly. "
12/01/2013 - "We further evaluated the treatment effects on different stroke subtypes among the three benidipine-based regimens. "
12/01/2013 - "Effects of a benidipine-based combination therapy on the risk of stroke according to stroke subtype: the COPE trial."

12/01/2020 - "Finally we conclude that benidipine seems to show more positive and promising results in the management of hypertensive patients with chronic kidney disease."
11/01/2011 - "One-year results of an open-label study on antiproteinuric effect of benidipine in elderly patients with chronic kidney disease."
01/01/2010 - "Multivariate analysis revealed hazard ratios for renal events to be significantly higher with chronic kidney disease (CKD) and lower with benidipine. "
11/01/2013 - "This subanalysis was conducted to compare the efficacy of three combination therapies in a subset of 834 patients with chronic kidney disease (CKD) (287 patients treated with benidpine-ARB, 283 patients treated with benidipine-BB and 264 patients treated with benidipine-TD). "
02/01/2007 - "These findings indicated that benidipine may be effective for reducing the risk of developing chronic kidney disease in patients with metabolic syndrome."

01/01/2008 - "Benidipine was welltolerated and effective in elderly Chinese patients with essential hypertension."
03/01/2008 - "The purpose of the present study was to investigate whether orally administered benidipine might influence the membrane function in patients with essential hypertension. "
03/01/2008 - "Electron paramagnetic resonance investigation on modulatory effect of benidipine on membrane fluidity of erythrocytes in essential hypertension."
10/01/2004 - "58 outpatients with essential hypertension were treated with benidipine 4-8 mg/day for 8 weeks. "
04/01/2002 - "Forty patients with untreated essential hypertension were given benidipine at a dose of 6 mg a day. "

12/01/2006 - "These results suggest that the treatment with benidipine may increase the endothelial differentiation of circulating EPCs and contribute to endothelial protection, prevention of cardiovascular disease, and/or an improvement of the prognosis after ischemic damage."
03/01/1999 - "It is suggested that benidipine is a potent and long-lasting calcium antagonist which may be useful for the treatment of elderly hypertensive patients with cardiovascular disease."
01/01/2018 - "This subanalysis of the COPE trial demonstrated that blood pressure-lowering regimens combining benidipine with an ARB, β-blocker or thiazide diuretic were similarly effective for the prevention of cardiac events in Japanese hypertensive outpatients."
01/01/2018 - "The main results of the COPE trial demonstrated that the incidences of hard cardiovascular composite endpoints and fatal or non-fatal strokes were significantly higher in the benidipine/β-blocker group than in the benidipine/thiazide group.Methods and Results:We further evaluated the treatment effects on different cardiac events among the 3 benidipine-based regimens.We"
01/01/2023 - "Benidipine, a wide range dihydropyridine calcium channel blocker, is used to prevent and treat cardiovascular diseases. "