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7-methyl-2'-deoxyguanosine 3'-monophosphate
Also Known As:
7-methyl-dGMP
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Purines: 651
Purine Nucleotides: 140
Guanine Nucleotides: 675
Deoxyguanine Nucleotides
7-methyl-2'-deoxyguanosine 3'-monophosphate: 1
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleotides: 15763
Purine Nucleotides: 140
Guanine Nucleotides: 675
Deoxyguanine Nucleotides
7-methyl-2'-deoxyguanosine 3'-monophosphate: 1
Deoxyribonucleotides: 132
Deoxyguanine Nucleotides
7-methyl-2'-deoxyguanosine 3'-monophosphate: 1
Related Diseases
1.
Genetic Predisposition to Disease (Genetic Predisposition)
06/21/1995 - "
Using DNA-adduct detection methods specific for 7-methyl-dGMP and PAH-dGMP, we sought to determine whether an inherited genetic susceptibility to cancer associated with certain carcinogen-metabolizing and detoxifying genes (e.g., cytochrome P450 and glutathione S-transferase) is related to DNA adduct formation in lung tissue.
"
2.
Neoplasms (Cancer)
06/21/1995 - "
Using DNA-adduct detection methods specific for 7-methyl-dGMP and PAH-dGMP, we sought to determine whether an inherited genetic susceptibility to cancer associated with certain carcinogen-metabolizing and detoxifying genes (e.g., cytochrome P450 and glutathione S-transferase) is related to DNA adduct formation in lung tissue.
"
3.
Lung Neoplasms (Lung Cancer)
06/21/1995 - "
Higher 7-methyl-dGMP adduct levels were associated with CYP2D6 genotypes (P = .01), consistent with the reports of the increased risk of lung cancer associated with this genotype.
"
Related Drugs and Biologics
1.
Cytochrome P-450 CYP2D6 (CYP2D6)
2.
DNA Adducts
3.
Glutathione Transferase (Glutathione S-Transferase)
4.
Cytochrome P-450 Enzyme System (Cytochrome P450)
5.
Carcinogens
6.
2'-deoxyguanosine 5'-phosphate (dGMP)