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MK-886

orally active leukotriene biosynthesis inhibitor
Also Known As:
1-((4-chlorophenyl)methyl)-3-((1,1-dimethylethyl)thio)-alpha, alpha-dimethyl-5-(1-methylethyl)-1H-indole-2-propanoic acid; 1H-indole-2-propanoic acid, 1-((4-chlorophenyl)methyl)-3-((1,1-dimethylethyl)thio)-alpha, alpha-dimethyl-5-(1-methylethyl)-; 1H-indole-2-propanoic acid, 1-((4-chlorophenyl)methyl)-3-((1,1-dimethylethyl)thio)-alpha,alpha-dimethyl-5-(1-methylethyl)-, sodium salt (1:1); 1H-indole-2-propanoic acid, 1-((4-chlorophenyl)methyl)-3-((1,1-dimethylethyl)thio)-alpha,alpha-dimethyl-5-(1-methylethyl)-, sodium salt, hydrate (1:1:1); 3-(1-(4-chlorobenzyl)-3-t-butylthio-5-isopropylindol-2-yl)-2,2-dimethylpropanoic acid; L 663536; L-663,536; L-663536; MK 886; MK-886 sodium monohydrate; MK-886 sodium salt; MK-886 sodium salt hydrate; MK-886 sodium salt monohydrate; MK886; MK886 sodium
Networked: 144 relevant articles (11 outcomes, 17 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Anderson, K M: 7 articles (01/2005 - 07/2000)
2. Harris, J E: 7 articles (01/2005 - 07/2000)
3. Hofmanová, Jirina: 4 articles (11/2008 - 06/2006)
4. Kozubík, Alois: 4 articles (11/2008 - 06/2006)
5. Alrefai, W A: 4 articles (01/2005 - 07/2000)
6. Arthur, Subha: 3 articles (04/2021 - 01/2018)
7. Sundaram, Uma: 3 articles (04/2021 - 01/2018)
8. Murphy, Robert C: 3 articles (06/2014 - 11/2009)
9. Jeun, Sin-Soo: 3 articles (02/2013 - 05/2010)
10. Kim, Seong Muk: 3 articles (02/2013 - 05/2010)

Related Diseases

1. Neoplasms (Cancer)
2. Asthma (Bronchial Asthma)
3. Pain (Aches)
4. Inflammation (Inflammations)
5. Wounds and Injuries (Trauma)

Related Drugs and Biologics

1. Arachidonate 5-Lipoxygenase (5 Lipoxygenase)
2. Leukotrienes
3. A 78773
4. Lipoxygenase Inhibitors
5. Indomethacin (Indometacin)
6. 5-Lipoxygenase-Activating Proteins
7. Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)
8. Proteins (Proteins, Gene)
9. Cyclooxygenase Inhibitors
10. zileuton (Zyflo)

Related Therapies and Procedures

1. Analgesia
2. Transplantation
3. Heart Transplantation (Grafting, Heart)
4. Photochemotherapy (Photodynamic Therapy)
5. Induced Hypothermia