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friedelin

Also Known As:

24,25,26-trinoroleanan-3-one, 5,9,13-trimethyl-, (4beta,5beta,8alpha,9beta,10alpha,13alpha,14beta)-; friedelan-3-one; friedelanone; friedeline

Networked: 23 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - Pentacyclic Triterpenes: 108
        Lupanes: 28
        friedelin: 23

Experts

1.	Duraipandiyan, Veeramuthu: 3 articles (03/2021 - 08/2011)
2.	Ignacimuthu, Savarimuthu: 3 articles (03/2021 - 08/2011)
3.	André, Tibiri: 2 articles (01/2017 - 01/2012)
4.	Jean, Koudou: 2 articles (01/2017 - 01/2012)
5.	Marius, Lompo: 2 articles (01/2017 - 01/2012)
6.	Noufou, Ouédraogo: 2 articles (01/2017 - 01/2012)
7.	Pierre, Guissou Innocent: 2 articles (01/2017 - 01/2012)
8.	Antonisamy, Paulrayer: 2 articles (03/2015 - 08/2011)
9.	Motaung, Keolebogile Shirley: 1 article (05/2022)
10.	Razwinani, Mapula: 1 article (05/2022)

Related Diseases

1.	Type 2 Diabetes Mellitus (MODY) 03/25/2021 - "This finding proved that friedelin has an anti-diabetic effect through insulin-dependent signaling cascade mechanism, thus it may lead to establishing a drug to treat type 2 diabetes mellitus." 03/01/2013 - "It was suggested that friedelin and lanosterol may be beneficial to mimic insulin action that would be useful in the treatment of diabetes type 2 patients."
2.	Leukemia 05/01/2020 - "Taken together, Friedelin may prove beneficial in the treatment of leukemia." 05/01/2020 - "Friedelin inhibits the growth and metastasis of human leukemia cells via modulation of MEK/ERK and PI3K/AKT signalling pathways."
3.	Ulcer 03/05/2015 - "The present study has clearly demonstrated the anti-ulcer potential of friedelin, these findings suggested that friedelin could be a new useful natural gastroprotective tool against gastric ulcer. " 10/01/2000 - "Evaluation in rats for antiulcer activity of friedelan-3beta-ol 1 and friedelin 2. The two triterpenes isolated from the leaves of Maytenus ilicifolia, did not decrease gastric ulcers when tested on indometacine induced ulcer model in rats."
4.	Stomach Ulcer (Gastric Ulcer) 03/05/2015 - "The present study has clearly demonstrated the anti-ulcer potential of friedelin, these findings suggested that friedelin could be a new useful natural gastroprotective tool against gastric ulcer. " 03/05/2015 - "Ethanol-induced gastric ulcer model was used to investigate the gastroprotective effects of friedelin. " 10/01/2000 - "Evaluation in rats for antiulcer activity of friedelan-3beta-ol 1 and friedelin 2. The two triterpenes isolated from the leaves of Maytenus ilicifolia, did not decrease gastric ulcers when tested on indometacine induced ulcer model in rats."
5.	Hypertrophy 05/01/2022 - "The study investigated the influence of friedelin, resinone, tingenone and betulin plant-based secondary metabolite compounds on cellular proliferation, extracellular matrix (ECM) components synthesis, expression of chondrogenic markers and maturation of differentiated chondrocytes (cell proliferation and hypertrophy) in porcine adipose-derived mesenchymal stem cells (pADMSCs) undergoing chondrogenic differentiation. "

Related Drugs and Biologics

1.	Insulin (Novolin)
2.	Lanosterol
3.	16-hydroxylup-20(29)-en-3-one
4.	tingenone
5.	betulin
6.	Triterpenes
7.	Carrageenan
8.	Stigmasterol
9.	Croton Oil
10.	Methanol (Carbinol)

Related Therapies and Procedures

1.	Intraperitoneal Injections
2.	Analgesia
3.	Oral Administration