factor IX Kawachinagano

retains propeptide region of 18 amino acids due to a substitution of Arg by Glu at position 4; activation of mutant factor by factor XIa in the presence of Ca ions is defective; causes severe hemophilia B & no detectable clotting activity

Also Known As:

factor IX KWC

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzyme Precursors: 724
  - Factor IX: 1840
    - factor IX Kawachinagano: 1
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Blood Coagulation Factors: 5376
      - Factor IX: 1840
        factor IX Kawachinagano: 1
  - Protein Precursors: 37
    - Enzyme Precursors: 724
      - Factor IX: 1840
        factor IX Kawachinagano: 1
Biological Factors: 2472
- Blood Coagulation Factors: 5376
  - Factor IX: 1840
    - factor IX Kawachinagano: 1

Related Diseases

1.	Hemophilia B (Haemophilia B) 06/01/1989 - "Factor IX Kawachinagano (KWC) is a mutant factor IX protein initially recognized in a patient with severe haemophilia B, who had 46% of normal factor IX antigen and no detectable clotting activity. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Factor IX (Coagulation Factor IX)
3.	Antigens