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I 278

structure given in first source

Also Known As:

I-278; Urea, N-(2-chloroethyl)-N'-(2-hydroxy-3-(2-nitro-1H-imidazol-1-yl)propyl)-N-nitroso-

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - Nitroimidazoles: 565
        I 278: 3

Experts

1.	Bickel, H: 1 article (04/2014)
2.	Brettschneider, C: 1 article (04/2014)
3.	Ernst, A: 1 article (04/2014)
4.	Fuchs, A: 1 article (04/2014)
5.	Jessen, F: 1 article (04/2014)
6.	Köhler, M: 1 article (04/2014)
7.	König, H-H: 1 article (04/2014)
8.	Luck, T: 1 article (04/2014)
9.	Luppa, M: 1 article (04/2014)
10.	Maier, W: 1 article (04/2014)

Related Diseases

1.	Dementia (Dementias) 04/01/2014 - "Among the randomly selected sample of 6619 patients, 3327 (50.3%) individuals participated in the study at baseline and 2810 (42.5%) at follow-up I. Of the 2492 patients without dementia included at follow-up I, 278 developed dementia (184 AD) over the subsequent follow-up interval of 4.5 years. "
2.	Miosis 10/01/1987 - "Bilateral stimulation of the sciatic nerves at intensities which evoked activity in fibres conducting at A beta conduction velocities (greater than 40 m/s), resulted in no change in blood pressure, pupil diameter or release of SP-l.i. Stimulation intensities which activate fibres conducting at velocities less than 2 m/s resulted in increased blood pressure, miosis and elevated release of SP-l.i. (278 +/- 16% of control). "
3.	Whooping Cough (Pertussis) 05/01/2005 - "Group A: untreated normal rats; Group B: normal rats administered by ANP (drug I) 278 mg/kg; Group C: normal rats administered by ANP subtracted CA and RG (drug II) 222.7 mg/kg; Group D: brain edema model rats established by unilateral common carotid artery injection of Bacillus pertussis 250 million/kg; Group E: model rats administered by ANP 278 mg/kg 1 hr before modeling; Group F: model rats administered by drug II 222.7 mg 1 hr before modeling. "
4.	Brain Edema (Cerebral Edema) 05/01/2005 - "Group A: untreated normal rats; Group B: normal rats administered by ANP (drug I) 278 mg/kg; Group C: normal rats administered by ANP subtracted CA and RG (drug II) 222.7 mg/kg; Group D: brain edema model rats established by unilateral common carotid artery injection of Bacillus pertussis 250 million/kg; Group E: model rats administered by ANP 278 mg/kg 1 hr before modeling; Group F: model rats administered by drug II 222.7 mg 1 hr before modeling. "

Related Drugs and Biologics

1.	Atrial Natriuretic Factor (ANF)