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amylinamide
has calcitonin-like effects; rat islet amyloid polypeptide with COOH-terminal amide
Also Known As:
IAPP amide; amylin-amide; insulinoma amyloid polypeptide amide
Networked:
3
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Macromolecular Substances: 97
Multiprotein Complexes: 125
Amyloid: 36214
amylinamide: 3
Amino Acids, Peptides, and Proteins: 1
Proteins: 484843
Amyloid: 36214
amylinamide: 3
Related Diseases
1.
Bone Resorption
07/01/1990 - "
In the present study, we have compared directly, the hypocalcaemic potency and duration of action of human amylin-amide and human calcitonin in an in vivo rat bioassay and an in vitro osteoclast bone resorption assay.
"
2.
Amyloid Plaque
01/01/1992 - "
In order to examine the effect of islet amyloid polypeptide (IAPP/amylin), a product of the pancreatic beta cell and a major component of islet amyloid deposits, on exocrine pancreatic function, we studied the effect of rat IAPP amide (IAPP-NH2) on 2-deoxy-D-glucose (2-DG) uptake in isolated mouse pancreatic acini.
"
03/01/1990 - "
Amylin amide, a 37-amino acid peptide that is a major component of amyloid deposits in the diabetic pancreas, possesses vasodilator activity.
"
3.
Edema (Dropsy)
03/01/1990 - "
Amylin amide did not induce edema formation; however, as a consequence of its vasodilator activity, amylin amide potentiated edema formation induced in rabbit skin by bradykinin.
"
Related Drugs and Biologics
1.
Calcitonin (Calcitonin, Eel)
2.
Islet Amyloid Polypeptide
3.
Vasodilator Agents (Vasodilators)
4.
Peptides (Polypeptides)
5.
Deoxyglucose (2 Deoxy D glucose)
6.
Bradykinin
7.
Acids