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2-hydroxyestradiol 17-sulfate

Also Known As:

2-OH-E2-17-S

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Estranes
      - Estrenes
        Estradiol: 14115
        2-hydroxyestradiol 17-sulfate: 3
Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Gonadal Hormones: 716
    - Gonadal Steroid Hormones: 7657
      - Estradiol Congeners: 358
        Estradiol: 14115
        2-hydroxyestradiol 17-sulfate: 3

Experts

1.	Takanashi, Kaori: 2 articles (08/2003 - 06/2003)
2.	Kyo, Takahiro: 1 article (08/2003)
3.	Osanai, Yasunori: 1 article (08/2003)
4.	Yoshizawa, Itsuo: 1 article (08/2003)
5.	Honjo, H: 1 article (03/2000)
6.	Honma, T: 1 article (03/2000)
7.	Kashiwagi, T: 1 article (03/2000)
8.	Takanashi, K: 1 article (03/2000)
9.	Yoshizawa, I: 1 article (03/2000)

Related Diseases

1.

Pre-Eclampsia (Preeclampsia)

06/01/2003 - "[Studies on 2-hydroxyestradiol 17-sulfate derived from fetoplacental unit: the antioxidant as a potential defense substance against preeclampsia]."
06/01/2003 - "The antioxidant 2-hydroxyestradiol 17-sulfate (2-OH-E2-17-S) was found to be present in the placenta and to prevent the onset of preeclampsia. "
03/01/2000 - "To investigate our hypothesis that 2-hydroxyestradiol 17-sulfate (2-OH-ES) is the placental antioxidant during pregnancy, we developed an assay for 2-OH-ES in urine and studied samples from women with and without preeclampsia. "
08/01/2003 - "Two endogenous antioxidants that are speculated to be defense substances against preeclampsia, 2-hydroxyestradiol (2-OH-E2) and its 17-sulfate, 2-hydroxyestradiol 17-sulfate (2-OH-E2-17-S), were administered to rats to compare their inhibitory effects on hepatic microsomal lipid peroxidation, and the lipid peroxides were determined in NADPH- and ascorbic acid-dependent systems. "

Related Drugs and Biologics

1.	Antioxidants
2.	NADP (NADPH)
3.	Lipid Peroxides
4.	Ascorbic Acid (Vitamin C)
5.	2-hydroxyestradiol