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homosalate

cpd not photoallergenic

Also Known As:

3,3,5-trimethylcyclohexyl salicylate; Benzoic acid, 2-hydroxy-, 3,3,5-trimethylcyclohexyl ester

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Conscience, M: 1 article (03/2001)
2.	Cotton, B: 1 article (03/2001)
3.	Haller, V: 1 article (03/2001)
4.	Lichtensteiger, W: 1 article (03/2001)
5.	Schlumpf, M: 1 article (03/2001)
6.	Steinmann, B: 1 article (03/2001)

Related Diseases

1.	Adrenocortical Carcinoma 12/01/2023 - "In this study, the effect of the toxicity of a binary mixture comprising avobenzone (0.72 μg L-1) and homosalate (1.02 and 103 μg L-1) on steroid hormone biosynthesis were investigated using male zebrafish and human adrenocortical carcinoma (H295R) cells. "
2.	Photoallergic Dermatitis (Photoallergy) 05/01/1990 - "Coumarin and homosalate, two agents not traditionally associated with causing photoallergy in humans or animals, did not demonstrate contact photoallergy using this model. " 04/01/1989 - "The potential of 3 sunscreens (p-aminobenzoic acid, 4-isopropyldibenzoylmethane and homosalate) and 2 known human photoallergens (musk ambrette and tetrachlorosalicylanilide) to cause photoallergy, phototoxicity, and/or contact sensitization was determined using a guinea pig photoallergy model, as previously described by Harber and associates. "
3.	Phototoxic Dermatitis (Phototoxicity) 04/01/1989 - "The potential of 3 sunscreens (p-aminobenzoic acid, 4-isopropyldibenzoylmethane and homosalate) and 2 known human photoallergens (musk ambrette and tetrachlorosalicylanilide) to cause photoallergy, phototoxicity, and/or contact sensitization was determined using a guinea pig photoallergy model, as previously described by Harber and associates. "
4.	Fatty Liver 12/01/2023 - "In fish exposed to homosalate, a significant decrease in the gonadosomatic index, testosterone level, and transcription of several genes (e.g, hsd3b2, cyp17a1, and hsd17b1) and a significant increase in the hepatosomatic index, liver steatosis, 17β-estradiol level, and transcription of vtg gene were observed. "
5.	Breast Neoplasms (Breast Cancer) 03/01/2001 - "In MCF-7 breast cancer cells, five out of six chemicals, that is, benzophenone-3 (Bp-3), homosalate (HMS), 4-methyl-benzylidene camphor (4-MBC), octyl-methoxycinnamate (OMC), and octyl-dimethyl-PABA (OD-PABA), increased cell proliferation with median effective concentrations (EC(50)) values between 1.56 and 3.73 microM, whereas butyl-methoxydibenzoylmethane (B-MDM) was inactive. "

Related Drugs and Biologics

1.	avobenzone (parsol 1789)
2.	Steroids
3.	Hormones (Hormone)
4.	4-Aminobenzoic Acid (4 Aminobenzoic Acid)
5.	octylmethoxycinnamate (octyl-methoxycinnamate)
6.	Testosterone (Sustanon)
7.	Sunscreening Agents (Sunscreens)
8.	Salicylates
9.	Camphor
10.	3 beta-hydroxysteroid dehydrogenase type II