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pazinaclone
structure given in first source
Also Known As:
2-(7-chloro-1,8-naphthyridin-2-yl)-3-((1,4-dioxa-8-azaspiro(4.5)dec-8-yl)carbonylmethyl)isoindolin-1-one; DN 2327; DN-2327
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Isoindoles: 18
pazinaclone: 2
Naphthyridines: 2
pazinaclone: 2
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Spiro Compounds: 2
pazinaclone: 2
Polycyclic Compounds: 6
Spiro Compounds: 2
pazinaclone: 2
Related Diseases
1.
Body Weight (Weight, Body)
10/01/1996 - "
During the substitution period, the decreases in body weight and food consumption in both S-(+)-DN-2327 and both diazepam groups were suppressed compared with those in the basal diet group.
"
10/01/1996 - "
After stopping the treatment, the body weight and food consumption in the diazepam 100 and 300 mg/kg groups tended to decrease or decreased to values lower than those in the control group, whereas these parameters in the S-(+)-DN-2327 30, 100 and 300 mg/kg groups were comparable to the control group values.
"
2.
Ataxia (Dyssynergia)
01/01/1991 - "
On the other hand, DN-2327 only slightly affected the motor coordination in mice and rats, as estimated by the inclined screen test and the climbing test, respectively; however, the compound attenuated the motor incoordination produced by diazepam.
"
Related Drugs and Biologics
1.
Diazepam (Valium)